Xiao-ting Fu

TL;DR: The results indicated that Cur-NPs showed enhanced therapeutic effects than that of curcumin in improving neurological function, reducing brain water content, and Evans blue dye extravasation after SAH, and revealed that the strategy of using Cur- NPs could be a promising way in improved neurological function in EBI after experimental rat SAH.

TL;DR: The findings suggested that Cur could effectively suppress Aβ-induced cytotoxicity and apoptosis by inhibition of ROS-mediated oxidative damage and regulation of ERK pathway, which validated its therapeutic potential in chemoprevention and chemotherapy of A β-induced neurotoxicity.

TL;DR: The results demonstrated that ATX suppressed Hcy-induced cardiotoxicity in vitro and in vivo by inhibiting mitochondrial dysfunction and oxidative damage, and validated the strategy of using ATX may be a highly efficient way to combat HCy-mediated human CVD.

TL;DR: In this paper, the growth suppressive effect and mechanism of caudatin on human glioma U251 and U87 cells were evaluated in vitro in both a time and dose-dependent manner.

TL;DR: Results provide evidence that cyanidin suppresses Aß-induced cytotoxicity, by preventing oxidative damage mediated by reactive oxide species, which in turn inhibits mitochondrial apoptosis, and demonstrates the therapeutic potential of cyanid in the prevention of oxidative stress-mediated Aß neurotoxicity.