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Xiaofeng Ji
Researcher at Huazhong University of Science and Technology
Publications - 3
Citations - 127
Xiaofeng Ji is an academic researcher from Huazhong University of Science and Technology. The author has contributed to research in topics: Gradient descent & CASP. The author has an hindex of 2, co-authored 3 publications receiving 111 citations.
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Journal ArticleDOI
Community-wide Evaluation of Methods for Predicting the Effect of Mutations on Protein-Protein Interactions
Rocco Moretti,Sarel J. Fleishman,Rudi Agius,Mieczyslaw Torchala,Paul A. Bates,Panagiotis L. Kastritis,João P. G. L. M. Rodrigues,Mikael Trellet,Alexandre M. J. J. Bonvin,Meng Cui,Marianne Rooman,Dimitri Gillis,Yves Dehouck,Iain H. Moal,Miguel Romero-Durana,Laura Pérez-Cano,Chiara Pallara,Brian Jimenez,Juan Fernández-Recio,Samuel C. Flores,Michael S. Pacella,Krishna Praneeth Kilambi,Jeffrey J. Gray,Petr Popov,Petr Popov,Sergei Grudinin,Sergei Grudinin,Juan Esquivel-Rodríguez,Daisuke Kihara,Nan Zhao,Dmitry Korkin,Xiaolei Zhu,Omar N. A. Demerdash,Julie C. Mitchell,Eiji Kanamori,Yuko Tsuchiya,Haruki Nakamura,Hasup Lee,Hahnbeom Park,Chaok Seok,Jamica Sarmiento,Shide Liang,Shusuke Teraguchi,Daron M. Standley,Hiromitsu Shimoyama,Genki Terashi,Mayuko Takeda-Shitaka,Mitsuo Iwadate,Hideaki Umeyama,Dmitri Beglov,David R. Hall,Dima Kozakov,Sandor Vajda,Brian G. Pierce,Howook Hwang,Thom Vreven,Zhiping Weng,Yangyu Huang,Haotian Li,Xiufeng Yang,Xiaofeng Ji,Shiyong Liu,Yi Xiao,Martin Zacharias,Sanbo Qin,Huan-Xiang Zhou,Sheng-You Huang,Xiaoqin Zou,Sameer Velankar,Joël Janin,Shoshana J. Wodak,David Baker +71 more
TL;DR: A community‐wide assessment of methods to predict the effects of mutations on protein–protein interactions found that large‐scale fitness landscapes should continue to provide an excellent test bed for continued evaluation of both existing and new prediction methodologies.
Journal ArticleDOI
Efficiently finding the minimum free energy path from steepest descent path.
TL;DR: The Steepest Descent Path (SDP) is used to accelerate the sampling of MFEP and the SHAKE algorithm and the Lagrangian multipliers are used to control the optimization of both SDP and MFEP.
Journal ArticleDOI
Structural modeling of human cardiac sodium channel pore domain.
Xiaofeng Ji,Yi Xiao,Shiyong Liu +2 more
TL;DR: A structural model for open-state pore domain of hNav1.5 built using single template ROSETTA-membrane homology modeling with the crystal structure of NavMs to explore molecular mechanism of a state-dependent drug binding and help designing new drugs is presented.