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Xiaokun Yu
Researcher at University of Michigan
Publications - 4
Citations - 127
Xiaokun Yu is an academic researcher from University of Michigan. The author has contributed to research in topics: Caenorhabditis elegans & Proteome. The author has an hindex of 3, co-authored 3 publications receiving 111 citations.
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Journal ArticleDOI
C. elegans SIRT6/7 homolog SIR-2.4 promotes DAF-16 relocalization and function during stress.
Wei Chung Chiang,Daniel X. Tishkoff,Bo Yang,Joshua T. Wilson-Grady,Xiaokun Yu,Travis Mazer,Mark Eckersdorff,Steven P. Gygi,David B. Lombard,Ao Lin Hsu +9 more
TL;DR: SIR-2.4 is identified as a critical regulator of DAF-16 specifically in the context of stress responses, and a novel role for acetylation is revealed, modulated by the antagonistic activities of CBP-1 and SIR- 2.4, in modulating D AF-16 localization and function.
Journal ArticleDOI
Integrin‐linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF‐1
Caroline Kumsta,Tsui Ting Ching,Mayuko Nishimura,Andrew Davis,Sara Gelino,Hannah H. Catan,Xiaokun Yu,Chu Chiao Chu,Binnan Ong,Siler H. Panowski,Nathan Baird,Rolf Bodmer,Ao Lin Hsu,Malene Hansen +13 more
TL;DR: Hsf‐1 is identified as a novel effector of the organismal response to reduced ILK levels and ILK inhibition regulates HSF‐1 in a cell nonautonomous fashion to enhance stress resistance and lifespan in C. elegans.
Journal ArticleDOI
Monitoring newly synthesized proteins over the adult life span of Caenorhabditis elegans
TL;DR: Monitoring newly synthesized proteins on a proteome scale in Caenorhabditis elegans over time during adulthood found that inhibiting the expression of atp-3 and ril-1 beginning in late adulthood is still effective to extend the life span of C. elegans.
Journal ArticleDOI
Compositional changes and ecological characteristics of earthworm mucus under different electrical stimuli
Huihui Huan,Xingming Wang,Zhaoxia Chu,Xiaokun Yu,Tingyu Fan,Gang Li,Xiaoping Xu,Quan Zhen,Luntao Sun,Zhongbing Dong,Shijiao Zha +10 more
TL;DR: In this paper , six voltage and current combinations were utilized to promote earthworm mucus production (5 V and 6 V at 10, 20 and 30 mA, respectively), to explore the compositional changes of the mucus produced under different electrical stimuli, and to propose the best electrical stimulation group and mucus fraction applicable to soil heavy metal pollution remediation and sludge reutilization.