X
Xiaolei Ze
Researcher at University of Aberdeen
Publications - 13
Citations - 2497
Xiaolei Ze is an academic researcher from University of Aberdeen. The author has contributed to research in topics: Biology & Medicine. The author has an hindex of 4, co-authored 6 publications receiving 2050 citations.
Papers
More filters
Journal ArticleDOI
Dominant and diet-responsive groups of bacteria within the human colonic microbiota.
Alan W. Walker,Jennifer Ince,Sylvia H. Duncan,Lucy M. I. Webster,Grietje Holtrop,Xiaolei Ze,David Stanley Brown,Mark D. Stares,Paul Scott,Aurore Bergerat,Petra Louis,Freda M McIntosh,Alexandra M. Johnstone,Gerald E. Lobley,Julian Parkhill,Harry J. Flint +15 more
TL;DR: Time courses obtained by targeted qPCR revealed that ‘blooms’ in specific bacterial groups occurred rapidly after a dietary change, and these were rapidly reversed by the subsequent diet.
Journal ArticleDOI
Ruminococcus bromii is a keystone species for the degradation of resistant starch in the human colon.
TL;DR: It is argued strongly that R. bromii has a pivotal role in fermentation of RS3 in the human large intestine, and that variation in the occurrence of this species and its close relatives may be a primary cause of variable energy recovery from this important component of the diet.
Journal ArticleDOI
Unique Organization of Extracellular Amylases into Amylosomes in the Resistant Starch-Utilizing Human Colonic Firmicutes Bacterium Ruminococcus bromii
Xiaolei Ze,Yonit Ben David,Jenny A. Laverde-Gomez,Bareket Dassa,Paul O. Sheridan,Sylvia H. Duncan,Petra Louis,Bernard Henrissat,Nathalie Juge,Nicole M. Koropatkin,Edward A. Bayer,Harry J. Flint +11 more
TL;DR: This organization of starch-degrading enzymes is unprecedented and provides the first example of cohesin-dockerin interactions being involved in an amylolytic system, which is referred to as an “amylosome.”
Journal ArticleDOI
Some are more equal than others: The role of “keystone” species in the degradation of recalcitrant substrates
TL;DR: Evidence is presented that Ruminococcus bromii has a superior ability to degrade certain forms of particulate resistant starch when compared with other highly abundant species of amylolytic bacteria found in the human colon and that this bacterium provides an example of a keystone species within the microbial community with respect to RS fermentation.
Journal ArticleDOI
Nondigestible Carbohydrates Affect Metabolic Health and Gut Microbiota in Overweight Adults after Weight Loss.
Alexandra M. Johnstone,Jennifer Kelly,Sheila Ryan,Reyna Romero-Gonzalez,Hannah McKinnon,C. L. Fyfe,Erik Näslund,Rubén López-Nicolás,Douwina Bosscher,Angela Bonnema,Carmen Frontela-Saseta,Gaspar Ros-Berruezo,Graham W. Horgan,Xiaolei Ze,Jo Harrold,Jason C.G. Halford,Silvia W. Gratz,Sylvia H. Duncan,Soraya P. Shirazi-Beechey,Harry J. Flint +19 more
TL;DR: The metabolic benefits, for overweight adults, from WL were maintained through a subsequent WM diet with higher total carbohydrate intake and inclusion of resistant starch in the WM diet altered gut microbiota composition positively and resulted in lower fasting glucose compared with the control, with no apparent change in appetite.