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Xiaomei Mo
Researcher at Chinese Ministry of Education
Publications - 6
Citations - 231
Xiaomei Mo is an academic researcher from Chinese Ministry of Education. The author has contributed to research in topics: Xanthone & Rhizosphere. The author has an hindex of 5, co-authored 6 publications receiving 183 citations. Previous affiliations of Xiaomei Mo include Ocean University of China.
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Journal ArticleDOI
Versixanthones A-F, Cytotoxic Xanthone-Chromanone Dimers from the Marine-Derived Fungus Aspergillus versicolor HDN1009.
Guangwei Wu,Guihong Yu,Tibor Kurtán,Attila Mándi,Jixing Peng,Xiaomei Mo,Ming Liu,Hui Li,Xinhua Sun,Jing Li,Tianjiao Zhu,Qianqun Gu,Dehai Li +12 more
TL;DR: Six unusual xanthone-chromanone dimers, versixanthones A-F (1-6), featuring different formal linkages of tetrahydroxanthone and 2,2-disubstituted chroman-4-one monomers, were isolated from a culture of the mangrove-derived fungus Aspergillus versicolor HDN1009 and exhibited cytotoxicities against the seven tested cancer cell lines.
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Diketopiperazine alkaloids from a mangrove rhizosphere soil derived fungus Aspergillus effuses H1-1
Huquan Gao,Weizhong Liu,Weizhong Liu,Tianjiao Zhu,Xiaomei Mo,Attila Mándi,Tibor Kurtán,Jing Li,Jing Ai,Qianqun Gu,Dehai Li +10 more
TL;DR: Effusin A (1), a spirobicyclic N,O-acetal derivative with an unprecedented 3',3a',5',6'-tetrahydrospiro[piperazine-2,2'-pyrano[2,3,4-de]chromene] ring system, and aSpiro-polyketide-diketopiperazine hybrid dihydrocryptoechinulin D (2) were isolated from a
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Hybrid isoprenoids from a reeds rhizosphere soil derived actinomycete Streptomyces sp. CHQ-64.
Qian Che,Tianjiao Zhu,Xin Qi,Attila Mándi,Tibor Kurtán,Xiaomei Mo,Jing Li,Qianqun Gu,Dehai Li +8 more
TL;DR: Drimentines G (3) showed strong cytotoxicity against human cancer cells lines with IC(50)'s down to 1.01 μM, while 1 and 2 showed no significant activity.
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Structure-based discovery of cytotoxic dimeric tetrahydroxanthones as potential topoisomerase I inhibitors from a marine-derived fungus.
Guangwei Wu,Xin Qi,Xiaomei Mo,Guihong Yu,Qiang Wang,Tianjiao Zhu,Qianqun Gu,Ming Liu,Jing Li,Dehai Li +9 more
TL;DR: Five new dimeric xanthones isolated from the mangrove-derived fungus Aspergillus vericolor showed Topo I inhibition properties and the most potent compound 1, an atropisomer of compound 2, was confirmed to inhibit Bottomo I-mediated DNA relaxation by targeting Topo II, thereby, arresting the cell cycle process and inducing necrosis in cancer cells.
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Anticancer efficacy and absorption, distribution, metabolism, and toxicity studies of aspergiolide A in early drug development.
TL;DR: Results indicate that aspergiolide A has anticancer activity targeting topoisomerase II, with a similar structure and mechanism to adriamycin, but with much lower toxicity.