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Xiaosi Gu
Researcher at Icahn School of Medicine at Mount Sinai
Publications - 87
Citations - 3912
Xiaosi Gu is an academic researcher from Icahn School of Medicine at Mount Sinai. The author has contributed to research in topics: Functional magnetic resonance imaging & Insular cortex. The author has an hindex of 27, co-authored 69 publications receiving 3142 citations. Previous affiliations of Xiaosi Gu include Mount Sinai Health System & University of Texas at Dallas.
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Journal ArticleDOI
Anterior Insular Cortex and Emotional Awareness
TL;DR: A model in which AIC serves two major functions: integrating bottom‐up interoceptive signals with top‐down predictions to generate a current awareness state and providing descending predictions to visceral systems that provide a point of reference for autonomic reflexes is proposed.
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Testing the behavioral interaction and integration of attentional networks.
TL;DR: It is found that whereas alerting improves overall response speed, it exerts negative influence on executive control under certain conditions, and the hypothesis of functional integration and interaction of these brain networks is supported.
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Attention and reality constraints on the neural processes of empathy for pain.
Xiaosi Gu,Shihui Han +1 more
TL;DR: The findings indicate that the involvement of the neural substrates underlying pain-related empathy is constrained by top-down attention and contextual reality of stimuli.
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Somatic and vicarious pain are represented by dissociable multivariate brain patterns.
Anjali Krishnan,Anjali Krishnan,Choong-Wan Woo,Luke J. Chang,Luke J. Chang,Luka Ruzic,Luka Ruzic,Xiaosi Gu,Xiaosi Gu,Marina López-Solà,Philip L. Jackson,Jesús Pujol,Jin Fan,Jin Fan,Tor D. Wager +14 more
TL;DR: Combining functional neuroimaging with multivariate pattern analyses, dissociable patterns that predicted somatic and vicarious pain intensity in out-of-sample individuals were identified, suggesting possible mechanisms underlying limitations in feeling others’ pain, and present new, more specific, brain targets for studying pain empathy.
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Anterior insular cortex is necessary for empathetic pain perception.
Xiaosi Gu,Zhixian Gao,Xingchao Wang,Xun Liu,Xun Liu,Robert T. Knight,Robert T. Knight,Patrick R. Hof,Jin Fan +8 more
TL;DR: Examining the perception of others' pain in patients with anterior insular cortex or anterior cingulate cortex lesions reveals a critical role of anterior Insular cortex in empathetic pain processing, support for a wide range of neuropsychiatric illnesses characterized by prominent deficits in higher-level social functioning.