Xiaoyu Yang

TL;DR: A combination of the increasing importance of fluorine-containing molecules and the successful development of bench stable, commercially available fluorine sources has brought the expansion offluorine chemistry into the mainstream organic synthesis community, resulting in an acceleration in the development of new fluorination methods and consequently in methods for the asymmetric introduction of fluoride.

TL;DR: A strategy for chemoselective methionine bioconjugation through redox reactivity, using oxaziridine-based reagents to achieve highly selective, rapid, and robust methamphetamineionine labeling under a range of biocompatible reaction conditions is reported.

TL;DR: Application of the present glycosylation protocol in the efficient synthesis of a cyclic triterpene tetrasaccharide have further demonstrated the versatility and efficacy of this new method, in that a novel chemoselective glyCosylation of the carboxylic acid and a new one-pot sequential glycosYLation sequence have been implemented.

TL;DR: A rationale for four tactics for the synthesis of glycoside synthesis, based on the stage at which the glycosidic bond is formed between the saccharide and the aglycone, are provided.

TL;DR: The direct asymmetric amination of α-substituted cyclic ketones catalyzed by a chiral phosphoric acid is reported, yielding products with a N-containing quaternary stereocenter in high yields and excellent enantioselectivities.