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Xin Liu
Researcher at Bengbu Medical College
Publications - 19
Citations - 936
Xin Liu is an academic researcher from Bengbu Medical College. The author has contributed to research in topics: Cell growth & Gene knockdown. The author has an hindex of 12, co-authored 19 publications receiving 663 citations. Previous affiliations of Xin Liu include Xi'an Jiaotong University.
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Journal ArticleDOI
A novel lncRNA MCM3AP-AS1 promotes the growth of hepatocellular carcinoma by targeting miR-194-5p/FOXA1 axis
Yufeng Wang,Liu Yang,Tianxiang Chen,Xin Liu,Yang Guo,Qiaojuan Zhu,Xiangmin Tong,Wei Yang,Qiuran Xu,Dongsheng Huang,Kangsheng Tu +10 more
TL;DR: A novel oncogenic lncRNA MCM3AP-AS1 is revealed, which is overexpressed in HCC and positively correlated with large tumor size, high tumor grade, advanced tumor stage and poor prognosis of HCC patients.
Journal ArticleDOI
HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma
Qiuran Xu,Jianfeng Tu,Changwei Dou,Jun Zhang,Liu Yang,Xin Liu,Kefeng Lei,Zhikui Liu,Yufeng Wang,Lijie Li,Hangxing Bao,Jiahui Wang,Kangsheng Tu +12 more
TL;DR: HSP90 potentiates the glycolysis and proliferation, reduces the apoptosis and thus enhances the growth of HCC cells through PKM2, and a combination of these proteins could strongly predict the poor prognosis of H CC patients.
Journal ArticleDOI
MicroRNA-1296 inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting SRPK1-mediated PI3K/AKT pathway.
Qiuran Xu,Xin Liu,Zhikui Liu,Zhenyu Zhou,Yufeng Wang,Jianfeng Tu,Lijie Li,Hangxing Bao,Liu Yang,Kangsheng Tu +9 more
TL;DR: It was found that the expression of miR-1296 was reduced in HCC tissues and cell lines, and it was associated with metastasis and recurrence of HCC, and the promoting effects of hypoxia on metastasis-to-mesenchymal transition (EMT) and EMT of H CC cells were reversed by miR -1296.
Journal ArticleDOI
LncRNA LINC00689 promotes the growth, metastasis and glycolysis of glioma cells by targeting miR-338-3p/PKM2 axis.
TL;DR: The results suggested that LINC00689/miR-338-3p/PKM2 axis might play an essential role in glioma progression.
Journal ArticleDOI
MicroRNA-876-5p inhibits epithelial-mesenchymal transition and metastasis of hepatocellular carcinoma by targeting BCL6 corepressor like 1.
Qiuran Xu,Qiaojuan Zhu,Zhenyu Zhou,Yufeng Wang,Xin Liu,Guozhi Yin,Xiangmin Tong,Kangsheng Tu +7 more
TL;DR: In this article, the authors reported that miR-876-5p/BCORL1 axis may represent as a novel therapeutic target for hepatocellular carcinoma (HCC) treatment.