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Yufeng Wang
Researcher at Xi'an Jiaotong University
Publications - 63
Citations - 2580
Yufeng Wang is an academic researcher from Xi'an Jiaotong University. The author has contributed to research in topics: Medicine & microRNA. The author has an hindex of 24, co-authored 45 publications receiving 1853 citations.
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Journal ArticleDOI
A novel lncRNA MCM3AP-AS1 promotes the growth of hepatocellular carcinoma by targeting miR-194-5p/FOXA1 axis
Yufeng Wang,Liu Yang,Tianxiang Chen,Xin Liu,Yang Guo,Qiaojuan Zhu,Xiangmin Tong,Wei Yang,Qiuran Xu,Dongsheng Huang,Kangsheng Tu +10 more
TL;DR: A novel oncogenic lncRNA MCM3AP-AS1 is revealed, which is overexpressed in HCC and positively correlated with large tumor size, high tumor grade, advanced tumor stage and poor prognosis of HCC patients.
Journal ArticleDOI
Long non-coding RNA CASC2 suppresses epithelial-mesenchymal transition of hepatocellular carcinoma cells through CASC2/miR-367/FBXW7 axis.
Yufeng Wang,Zhikui Liu,Bowen Yao,Qing Li,Liang Wang,Cong Wang,Changwei Dou,Meng Xu,Qingguang Liu,Kangsheng Tu +9 more
TL;DR: Clinically, CASC2 underexpression and miR-367 overexpression were closely correlated with the metastasis-associated clinicopathologic features and it is concluded that the CASC 2/miR- 367/FBXW7 axis may be a ponderable and promising therapeutic target for HCC.
Journal ArticleDOI
HSP90 promotes cell glycolysis, proliferation and inhibits apoptosis by regulating PKM2 abundance via Thr-328 phosphorylation in hepatocellular carcinoma
Qiuran Xu,Jianfeng Tu,Changwei Dou,Jun Zhang,Liu Yang,Xin Liu,Kefeng Lei,Zhikui Liu,Yufeng Wang,Lijie Li,Hangxing Bao,Jiahui Wang,Kangsheng Tu +12 more
TL;DR: HSP90 potentiates the glycolysis and proliferation, reduces the apoptosis and thus enhances the growth of HCC cells through PKM2, and a combination of these proteins could strongly predict the poor prognosis of H CC patients.
Journal ArticleDOI
MicroRNA-1296 inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting SRPK1-mediated PI3K/AKT pathway.
Qiuran Xu,Xin Liu,Zhikui Liu,Zhenyu Zhou,Yufeng Wang,Jianfeng Tu,Lijie Li,Hangxing Bao,Liu Yang,Kangsheng Tu +9 more
TL;DR: It was found that the expression of miR-1296 was reduced in HCC tissues and cell lines, and it was associated with metastasis and recurrence of HCC, and the promoting effects of hypoxia on metastasis-to-mesenchymal transition (EMT) and EMT of H CC cells were reversed by miR -1296.
Journal ArticleDOI
Long non-coding RNA DSCR8 acts as a molecular sponge for miR-485-5p to activate Wnt/β-catenin signal pathway in hepatocellular carcinoma
Yufeng Wang,Liankang Sun,Liang Wang,Zhikui Liu,Qing Li,Bowen Yao,Cong Wang,Tianxiang Chen,Kangsheng Tu,Qingguang Liu +9 more
TL;DR: It is reported for the first time that D SCR8 activates Wnt/β-catenin signal pathway to promote HCC progression by DSCR8/miR-485-5p/FZD7 axis, providing promising and valuable strategies for targeted therapy of HCC.