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Xin Qu
Researcher at University of California, San Diego
Publications - 25
Citations - 3380
Xin Qu is an academic researcher from University of California, San Diego. The author has contributed to research in topics: 3D bioprinting & Cellular differentiation. The author has an hindex of 17, co-authored 25 publications receiving 2589 citations. Previous affiliations of Xin Qu include Novartis & Rensselaer Polytechnic Institute.
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Journal ArticleDOI
Deterministically patterned biomimetic human iPSC-derived hepatic model via rapid 3D bioprinting
Xuanyi Ma,Xin Qu,Wei Zhu,Yi-Shuan Li,Suli Yuan,Hong Zhang,Justin Liu,Pengrui Wang,Cheuk Sun Edwin Lai,Fabian Zanella,Gen-Sheng Feng,Farah Sheikh,Shu Chien,Shaochen Chen +13 more
TL;DR: 3D hydrogel-based triculture model that embeds hiPSC-HPCs with human umbilical vein endothelial cells and adipose-derived stem cells in a microscale hexagonal architecture is presented and finds improved morphological organization, higher liver-specific gene expression levels, increased metabolic product secretion, and enhanced cytochrome P450 induction.
Journal ArticleDOI
Biomimetic 3D-printed scaffolds for spinal cord injury repair
Jacob Koffler,Wei Zhu,Xin Qu,Oleksandr Platoshyn,Jennifer N. Dulin,John H. Brock,Lori Graham,Paul Lu,Jeff Sakamoto,Martin Marsala,Shaochen Chen,Mark H. Tuszynski,Mark H. Tuszynski +12 more
TL;DR: It is found that injured host axons regenerate into 3D biomimetic scaffolds and synapse onto NPCs implanted into the device and that implanted NPCs in turn extend axons out of the scaffold and into the host spinal cord below the injury to restore synaptic transmission and significantly improve functional outcomes.
Journal ArticleDOI
Direct 3D bioprinting of prevascularized tissue constructs with complex microarchitecture.
Wei Zhu,Xin Qu,Jie Zhu,Xuanyi Ma,Sherrina Patel,Justin Liu,Pengrui Wang,Cheuk Sun Edwin Lai,Maling Gou,Yang Xu,Kang Zhang,Shaochen Chen +11 more
TL;DR: This work created prevascularized tissues with complex three-dimensional (3D) microarchitectures using a rapid biop printing method - microscale continuous optical bioprinting (μCOB) that can be broadly applicable to the engineering and translation of various functional tissues.
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Rapid Fabrication of Complex 3D Extracellular Microenvironments by Dynamic Optical Projection Stereolithography
A. Ping Zhang,A. Ping Zhang,Xin Qu,Pranav Soman,Kolin C. Hribar,Jin W. Lee,Shaochen Chen,Sailing He +7 more
TL;DR: A novel biofabrication method using a digital-mirror device (DMD), called dynamic optical projection stereolithography (DOPsL) is demonstrated, which can generate complex biomimetic scaffolds within seconds.
Journal ArticleDOI
3D optical printing of piezoelectric nanoparticle-polymer composite materials.
TL;DR: It is demonstrated that efficient piezoelectric nanoparticle-polymer composite materials can be optically printed into three-dimensional (3D) microstructures using digital projection printing and lays the groundwork for creating highly efficient pieZoelectrics polymer materials via nanointerfacial tuning.