Xin Qu

TL;DR: 3D hydrogel-based triculture model that embeds hiPSC-HPCs with human umbilical vein endothelial cells and adipose-derived stem cells in a microscale hexagonal architecture is presented and finds improved morphological organization, higher liver-specific gene expression levels, increased metabolic product secretion, and enhanced cytochrome P450 induction.

TL;DR: It is found that injured host axons regenerate into 3D biomimetic scaffolds and synapse onto NPCs implanted into the device and that implanted NPCs in turn extend axons out of the scaffold and into the host spinal cord below the injury to restore synaptic transmission and significantly improve functional outcomes.

TL;DR: This work created prevascularized tissues with complex three-dimensional (3D) microarchitectures using a rapid biop printing method - microscale continuous optical bioprinting (μCOB) that can be broadly applicable to the engineering and translation of various functional tissues.

TL;DR: A novel biofabrication method using a digital-mirror device (DMD), called dynamic optical projection stereolithography (DOPsL) is demonstrated, which can generate complex biomimetic scaffolds within seconds.

TL;DR: It is demonstrated that efficient piezoelectric nanoparticle-polymer composite materials can be optically printed into three-dimensional (3D) microstructures using digital projection printing and lays the groundwork for creating highly efficient pieZoelectrics polymer materials via nanointerfacial tuning.