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Xin Wang
Researcher at Jilin University
Publications - 2
Citations - 95
Xin Wang is an academic researcher from Jilin University. The author has contributed to research in topics: CD8 & T cell. The author has an hindex of 2, co-authored 2 publications receiving 46 citations.
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Photodynamic therapy produces enhanced efficacy of antitumor immunotherapy by simultaneously inducing intratumoral release of sorafenib.
Xu Sun,Ziyang Cao,Kuirong Mao,Chenxi Wu,Hongmei Chen,Jialiang Wang,Xin Wang,Xiuxiu Cong,Li Yong,Xianying Meng,Xianzhu Yang,Yong-Guang Yang,Tianmeng Sun +12 more
TL;DR: A rapidly released sorafenib acts synergistically with the low-dose PDT to inhibit tumor growth by inducing strong T cell-dependent local and systemic antitumor immune responses, reprograming the tumor immune microenvironment, and limiting the interaction between cytotoxic CD8+ T cells and immunosuppressive cells.
Journal ArticleDOI
Intratumoral delivery of CCL25 enhances immunotherapy against triple-negative breast cancer by recruiting CCR9+ T cells
Hongmei Chen,Xiuxiu Cong,Chenxi Wu,Xuan Wu,Jialiang Wang,Kuirong Mao,Jie Li,Ge Zhu,Feiqi Liu,Xiandi Meng,Jia Song,Xu Sun,Xin Wang,Shuhan Liu,Shi Zhang,Xianzhu Yang,Yanqiu Song,Yong-Guang Yang,Tianmeng Sun +18 more
TL;DR: It is found that CCL25, the only chemokine for CCR9+ cells, is not expressed in human or murine triple-negative breast cancers (TNBCs), raising a hypothesis that intratumoral delivery of CCL 25 may enhance antitumor immunotherapy in TNBCs.