T
Tianmeng Sun
Researcher at Jilin University
Publications - 67
Citations - 6545
Tianmeng Sun is an academic researcher from Jilin University. The author has contributed to research in topics: Drug delivery & Medicine. The author has an hindex of 27, co-authored 49 publications receiving 5523 citations. Previous affiliations of Tianmeng Sun include The Wallace H. Coulter Department of Biomedical Engineering & University of Science and Technology of China.
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Engineered Nanoparticles for Drug Delivery in Cancer Therapy
TL;DR: It is anticipated that precisely engineered nanoparticles will emerge as the next-generation platform for cancer therapy and many other biomedical applications.
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Doxorubicin-tethered responsive gold nanoparticles facilitate intracellular drug delivery for overcoming multidrug resistance in cancer cells.
TL;DR: DOX-Hyd@AuNPs represents a model with dual roles in overcoming MDR in cancer cells and probing the intracellular release of drug from its delivery system.
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A tumor-acidity-activated charge-conversional nanogel as an intelligent vehicle for promoted tumoral-cell uptake and drug delivery.
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Simultaneous Delivery of siRNA and Paclitaxel via a “Two-in-One” Micelleplex Promotes Synergistic Tumor Suppression
Tianmeng Sun,Jin-Zhi Du,Yandan Yao,Chengqiong Mao,Shuang Dou,Songyin Huang,Pei-Zhuo Zhang,Kam W. Leong,Erwei Song,Jun Wang +9 more
TL;DR: Clear evidence is shown that the micelleplex is capable of delivering siRNA and paclitaxel simultaneously to the same tumoral cells both in vitro and in vivo and can induce a synergistic tumor suppression effect in the MDA-MB-435s xenograft murine model.
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Gold nanoparticles capped with polyethyleneimine for enhanced siRNA delivery.
TL;DR: Without exhibiting cellular toxicity, PEI-capped AuNPs appear to be suitable as a potential carrier for intracellular siRNA delivery.