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Xinfu Zhang
Researcher at Dalian University of Technology
Publications - 75
Citations - 2343
Xinfu Zhang is an academic researcher from Dalian University of Technology. The author has contributed to research in topics: Chemistry & Medicine. The author has an hindex of 23, co-authored 57 publications receiving 1455 citations. Previous affiliations of Xinfu Zhang include Ohio State University.
Papers
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Journal ArticleDOI
Long-Wavelength, Photostable, Two-Photon Excitable BODIPY Fluorophores Readily Modifiable for Molecular Probes
TL;DR: Comparison of single-molecular imaging confirms that DPC is a much more efficient and more photostable NIR fluorophore than the commonly used Cy5 and demonstrates its utility as a standard colocalizing agent to estimate the other probes' local distribution.
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Replacing Phenyl Ring with Thiophene: An Approach to Longer Wavelength Aza-dipyrromethene Boron Difluoride (Aza-BODIPY) Dyes
Xinfu Zhang,Haibo Yu,Yi Xiao +2 more
TL;DR: In the orignial 1,3,5,7-tetraphenyl aza-BODIPY, replacing the phenyl rings with thiophene achieved significant bathochromic shifts and one of the target molecules, DPDTAB, emitting strong NIR fluorescence with a quantum yield of 0.46 in acetonitrile, is a very competitive NIR fluorophore.
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Nanoscale platforms for messenger RNA delivery.
Bin Li,Xinfu Zhang,Yizhou Dong +2 more
TL;DR: This review focuses on recent advances, challenges, and future directions in nanoscale platforms designed for mRNA delivery, including lipid and lipid-derived nanoparticles, polymer-based nanop articles, protein derivatives mRNA complexes, and other types of nanomaterials.
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Vitamin lipid nanoparticles enable adoptive macrophage transfer for the treatment of multidrug-resistant bacterial sepsis
Xucheng Hou,Xinfu Zhang,Xinfu Zhang,Weiyu Zhao,Chunxi Zeng,Binbin Deng,David W. McComb,Shi Du,Chengxiang Zhang,Wenqing Li,Yizhou Dong +10 more
TL;DR: It is shown that adoptive transfer of macrophages containing antimicrobial peptides linked to cathepsin B in the lysosomes can be applied for the treatment of multidrug-resistant bacteria-induced sepsis in mice with immunosuppression.
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Engineering CRISPR–Cpf1 crRNAs and mRNAs to maximize genome editing efficiency
TL;DR: Engineered CRISPR-Cpf1 systems should facilitate a broad range of genome editing applications and it is discovered that 11 out of 16 crRNAs from Cpf 1 orthologs enabled genome editing in the presence of AsCPf1.