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Xingde Li
Researcher at Johns Hopkins University
Publications - 291
Citations - 18785
Xingde Li is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Optical coherence tomography & Endomicroscopy. The author has an hindex of 60, co-authored 280 publications receiving 17610 citations. Previous affiliations of Xingde Li include Kennedy Krieger Institute & Institute for Systems Biology.
Papers
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Journal ArticleDOI
Biodegradable Stimuli-Responsive Polymeric Micelles for Treatment of Malignancy.
Lesan Yan,Xingde Li +1 more
TL;DR: This review highlights recent advances concerning stimuli-responsive micelles made of biodegradable polypeptide and polyester as nanocarries for drug delivery, and limits the content to pH sensitive, redox sensitive, and photo-sensitive micellar systems for safe and efficient cancer chemotherapy.
Journal ArticleDOI
AI-Assisted In Situ Detection of Human Glioma Infiltration Using a Novel Computational Method for Optical Coherence Tomography
Ronald M. Juarez-Chambi,Carmen Kut,Jose J. Rico-Jimenez,Kaisorn L. Chaichana,Jiefeng Xi,Daniel U. Campos-Delgado,Fausto J. Rodriguez,Alfredo Quinones-Hinojosa,Xingde Li,Javier A. Jo +9 more
TL;DR: A novel artificial intelligence (AI)-assisted method for automated, real-time, in situ detection of glioma infiltration at high spatial resolution and excellent levels of sensitivity and specificity for detectingglioma-infiltrated brain tissue.
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Parallel deep neural networks for endoscopic OCT image segmentation
Dawei Li,Jimin Wu,Yufan He,Xinwen Yao,Wu Yuan,Defu Chen,Hyeon Cheol Park,Shaoyong Yu,Jerry L. Prince,Xingde Li +9 more
TL;DR: Parallel-trained deep neural networks for automated endoscopic OCT image segmentation feasible even with a limited training data set are reported and quantitative changes in the top esophageal layers' thickness in the EOE model are demonstrated.
Journal ArticleDOI
Allergen challenge sensitizes TRPA1 in vagal sensory neurons and afferent C-fiber subtypes in guinea pig esophagus.
Zhenyu Liu,Youtian Hu,Xiaoyun Yu,Jiefeng Xi,Xiaoming Fan,Chung-Ming Tse,Allen C. Myers,Pankaj J. Pasricha,Xingde Li,Shaoyong Yu +9 more
TL;DR: In this paper, a guinea pig model of eosinophilic esophagitis (EoE) was used to determine whether prolonged antigen exposure in vivo sensitizes transient receptor potential A1 (TRPA1) in esophageal vagal nodose C fibers.
Journal ArticleDOI
Fiber-optic nonlinear endomicroscopy with focus scanning by using shape memory alloy actuation.
TL;DR: A miniature fiber optic endomicroscope with built-in dynamic focus scanning capability is developed for the first time for 3-D two-photon fluorescence (TPF) imaging of biological samples and the results demonstrate the feasibility of3-D nonlinear optical imaging with the SMA-based scanning fiber-optic endomicrobialscope.