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Xingde Li
Researcher at Johns Hopkins University
Publications - 291
Citations - 18785
Xingde Li is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Optical coherence tomography & Endomicroscopy. The author has an hindex of 60, co-authored 280 publications receiving 17610 citations. Previous affiliations of Xingde Li include Kennedy Krieger Institute & Institute for Systems Biology.
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Journal ArticleDOI
Imaging needle for optical coherence tomography
TL;DR: A miniature optical coherence tomography (OCT) imaging needle that can be inserted into solid tissues and organs to permit interstitial imaging of their internal microstructures with micrometer scale resolution and minimal trauma is described.
Journal ArticleDOI
Fluorescence lifetime imaging in turbid media
TL;DR: The inverse problem for f luorescence lifetime tomography is formulated using diffuse photon density waves, and the technique is demonstrated by deriving spatial images of heterogeneous f l luorophore distribution and lifetime, using simulated measurements in heterogeneous turbid media.
Journal ArticleDOI
Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus.
Xingde Li,Stephen A. Boppart,Stephen A. Boppart,J. Van Dam,Hiroshi Mashimo,Hiroshi Mashimo,Muthoka L. Mutinga,Wolfgang Drexler,M. Klein,Costas Pitris,Costas Pitris,Mary L. Krinsky,Mark E. Brezinski,James G. Fujimoto +13 more
TL;DR: OCT technology with compact fiberoptic imaging probes can be used as an adjunct to endoscopy for real-time image-guided evaluation of Barrett's esophagus and suggests future potential for resolution and contrast enhancements in clinical studies.
Journal ArticleDOI
A quantitative study on the photothermal effect of immuno gold nanocages targeted to breast cancer cells.
TL;DR: It was found that cells targeted with the immuno Au nanocages responded immediately to laser irradiation and that the cellular damage was irreversible at power densities greater than 1.6 W/cm(2), and the percentage of dead cells increased with increasing exposure time up to 5 min and then became steady.
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Fiber-optic scanning two-photon fluorescence endoscope.
TL;DR: The development of a miniature, flexible, fiber-optic scanning endoscope for two-photon fluorescence imaging using a tubular piezoelectric actuator for achieving two-dimensional beam scanning and a double-clad fiber for delivery of the excitation light and collection of two-Photon Fluorescence.