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Xinghai Chen
Researcher at St. Mary's University
Publications - 12
Citations - 603
Xinghai Chen is an academic researcher from St. Mary's University. The author has contributed to research in topics: Apoptosis & Oxidative stress. The author has an hindex of 6, co-authored 12 publications receiving 197 citations.
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Journal ArticleDOI
The adverse health effects of bisphenol A and related toxicity mechanisms.
Ya Ma,Haohao Liu,Jinxia Wu,Le Yuan,Yueqin Wang,Xingde Du,Rui Wang,Phelisters Wegesa Marwa,Pavankumar Petlulu,Xinghai Chen,Huizhen Zhang +10 more
TL;DR: The underlying mechanisms of BPA-induced multi-organ toxicity were well summarized, involving the receptor pathways, disruption of neuroendocrine system, inhibition of enzymes, modulation of immune and inflammatory responses, as well as genotoxic and epigenetic mechanisms.
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The Diversity of Cyanobacterial Toxins on Structural Characterization, Distribution and Identification: A Systematic Review.
Xingde Du,Haohao Liu,Le Yuan,Yueqin Wang,Ya Ma,Rui Wang,Xinghai Chen,Michael D. Losiewicz,Hongxiang Guo,Huizhen Zhang +9 more
TL;DR: This communication provides a comprehensive review of the diversity of cyanotoxins, and the detection and identification technology was discussed and will be a valuable resource for identifying the various types of cyanOToxins which threaten the environment of different areas.
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The latest advances in the reproductive toxicity of microcystin-LR.
Shiyu Zhang,Xingde Du,Haohao Liu,Michael D. Losiewic,Xinghai Chen,Ya Ma,Rui Wang,Zhihui Tian,Linjia Shi,Hongxiang Guo,Huizhen Zhang +10 more
TL;DR: This paper proposes for the first time that MC-LR can produce estrogenic effects in animals as an environmental estrogen and could be an important direction for future research.
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Update on the adverse effects of microcystins on the liver.
Linjia Shi,Xingde Du,Haohao Liu,Xinghai Chen,Ya Ma,Rui Wang,Zhihui Tian,Shiyu Zhang,Hongxiang Guo,Huizhen Zhang +9 more
TL;DR: The latest evidence shows that epigenetic modifications may play an important role in MCs-induced liver cancer and the imbalance of liver metabolic homeostasis may be involved in the hepatotoxicity induced by MCs.
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Histone acetylation plays an important role in MC-LR-induced apoptosis and cycle disorder in SD rat testicular cells.
Yueqin Wang,Haohao Liu,Xiaohui Liu,Xiaofeng Zhang,Jinxia Wu,Le Yuan,Xingde Du,Rui Wang,Ya Ma,Xinghai Chen,Xuemin Cheng,Donggang Zhuang,Huizhen Zhang +12 more
TL;DR: Results indicated that MC-LR could activate the mitochondrial apoptotic pathway and disorder the cell cycle pathway to induce the cell apoptosis by enhancing HDAC activity and reducing histone acetylation of normal testicular cells in SD rats, which provides a new insight on the reproductive toxicity of male induced byMC-LR.