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Xinmin Yao
Researcher at Peking University
Publications - 6
Citations - 1438
Xinmin Yao is an academic researcher from Peking University. The author has contributed to research in topics: Coronavirus & Internal medicine. The author has an hindex of 4, co-authored 5 publications receiving 1102 citations.
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Journal ArticleDOI
On the origin and continuing evolution of SARS-CoV-2
Xiaolu Tang,Changcheng Wu,Xiang Li,Yuhe Song,Yuhe Song,Xinmin Yao,Xinkai Wu,Yuange Duan,Hong Zhang,Yirong Wang,Zhaohui Qian,Jie Cui,Jian Lu +12 more
TL;DR: The results suggest that the development of new variations in functional sites in the receptor-binding domain (RBD) of the spike seen in SARS-CoV-2 and viruses from pangolin SARSr-CoVs are likely caused by natural selection besides recombination.
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The evolutionary arms race between transposable elements and piRNAs in Drosophila melanogaster
TL;DR: The results suggest the emergence, repression specificity and strength of piRNAs on TEs should be considered in studying the landscapes of TE insertions in Drosophila, and also provide novel insights into the nature of genomic conflicts of other forms.
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Evolutionary analysis and lineage designation of SARS-CoV-2 genomes.
Xiaolu Tang,Ruochen Ying,Xinmin Yao,Guanghao Li,Guanghao Li,Changcheng Wu,Yiyuli Tang,Zhida Li,Bishan Kuang,Feng Wu,Changsheng Chi,Xiaoman Du,Yi Qin,Shenghan Gao,Songnian Hu,Juncai Ma,Tiangang Liu,Xinghuo Pang,Jianwei Wang,Guoping Zhao,Wenjie Tan,Ya-Ping Zhang,Xuemei Lu,Jian Lu +23 more
TL;DR: Wang et al. as discussed by the authors analyzed single nucleotide variants (SNVs) in 121,618 high-quality SARS-CoV-2 genomes and divided these viral genomes into two major lineages (L and S) based on variants at sites 8782 and 28144.
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The use of SARS-CoV-2-related coronaviruses from bats and pangolins to polarize mutations in SARS-Cov-2.
TL;DR: Forward simulations of the molecular evolution of viral genomes by incorporating mutations and natural selection and the effect of sequence similarity between the outgroup and ingroup lineages on the accuracy of ancestral allele inference are evaluated.
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The concordance between the evolutionary trend and the clinical manifestation of the two SARS-CoV-2 variants.
Ben Hu,Ran Liu,Xiaolu Tang,Yuchen Pan,Ming Wang,Yongqing Tong,Guangming Ye,Gaigai Shen,Ruochen Ying,Aisi Fu,Di Li,Wanxu Zhao,Jing Peng,Jie Guo,Dong Men,Xinmin Yao,Yirong Wang,Hong Zhang,Zhihui Feng,Junping Yu,Liangjun Chen,Zixin Deng,Xuemei Lu,Ya-Ping Zhang,Yirong Li,Bende Liu,Lilei Yu,Yan Li,Jian Lu,Tiangang Liu +29 more