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Jie Cui

Researcher at Chinese Academy of Sciences

Publications -  172
Citations -  10055

Jie Cui is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 30, co-authored 89 publications receiving 7376 citations. Previous affiliations of Jie Cui include Pasteur Institute & Hebei Normal University.

Papers
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Origin and evolution of pathogenic coronaviruses

TL;DR: The viral factors that enabled the emergence of diseases such as severe acute respiratory syndrome and Middle East respiratory syndrome are explored and the diversity and potential of bat-borne coronaviruses are highlighted.
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On the origin and continuing evolution of SARS-CoV-2

TL;DR: The results suggest that the development of new variations in functional sites in the receptor-binding domain (RBD) of the spike seen in SARS-CoV-2 and viruses from pangolin SARSr-CoVs are likely caused by natural selection besides recombination.
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Comparative genomics reveals insights into avian genome evolution and adaptation.

Guojie Zhang, +106 more
- 12 Dec 2014 - 
TL;DR: This work explored bird macroevolution using full genomes from 48 avian species representing all major extant clades to reveal that pan-avian genomic diversity covaries with adaptations to different lifestyles and convergent evolution of traits.
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Discovery of a rich gene pool of bat SARS-related coronaviruses provides new insights into the origin of SARS coronavirus

TL;DR: It is hypothesized that the direct progenitor of SARS-CoV may have originated after sequential recombination events between the precursors of these SARSr-CoVs, and highlights the necessity of preparedness for future emergence of Sars-like diseases.
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Contraction of the type I IFN locus and unusual constitutive expression of IFN-α in bats.

TL;DR: It is demonstrated that bat IFN-α genes are constitutively expressed in unstimulated bat tissues and cells and their expression is unaffected by viral infection, providing evidence for a unique IFN system that may be linked to the ability of bats to coexist with viruses.