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Xiujuan Qu
Researcher at China Medical University (PRC)
Publications - 212
Citations - 4124
Xiujuan Qu is an academic researcher from China Medical University (PRC). The author has contributed to research in topics: Cancer & Cancer cell. The author has an hindex of 31, co-authored 191 publications receiving 3038 citations.
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Journal ArticleDOI
Gastric cancer exosomes promote tumour cell proliferation through PI3K/Akt and MAPK/ERK activation.
Jinglei Qu,Xiujuan Qu,Mingfang Zhao,Yuee Teng,Ye Zhang,Kezuo Hou,You-Hong Jiang,Xianghong Yang,Yunpeng Liu +8 more
TL;DR: Gastric cancer exosomes promoted tumour cell proliferation, at least in part, by activation of PI3K/Akt and mitogen-activated protein kinase/extracellular-regulatedprotein kinase pathways.
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β-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis
TL;DR: The authors' data provides the first evidence that β-elemene induces protective autophagy and prevents human gastric cancer cells from undergoing apoptosis, and a combination of β- elemene with autophagic inhibitor might thus be a useful therapeutic option for advanced Gastric cancer.
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Exosomal PD-L1 Retains Immunosuppressive Activity and is Associated with Gastric Cancer Prognosis
Yibo Fan,Xiaofang Che,Jinglei Qu,Kezuo Hou,Ti Wen,Zhi Li,Ce Li,Shuo Wang,Ling Xu,Yunpeng Liu,Xiujuan Qu +10 more
TL;DR: Overall, exosomal PD-L1 predicts the worse survival and reflects the immune status in GC patients, resulting from a stronger T-cell dysfunction due to its stable and MHC-I expression.
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Microsatellite instability and survival in gastric cancer: A systematic review and meta-analysis.
TL;DR: Gastric cancers treated with high-frequency microsatellite instability (MSI-H) have an improved prognosis, accompanied with reduced risk of LN metastasis, tumor invasion and mortality, and the main outcome was the overall survival rate.
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IGF-IR signaling in epithelial to mesenchymal transition and targeting IGF-IR therapy: Overview and new insights
TL;DR: This review summarizes the regulation of EMT by IGF-I/IGF-IR signaling pathway and drug resistance mechanisms of targeting IGF-IR therapy and addresses several factors in the regulation that may be potential predictive biomarkers in targeted therapy.