β-Elemene-induced autophagy protects human gastric cancer cells from undergoing apoptosis
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TLDR
The authors' data provides the first evidence that β-elemene induces protective autophagy and prevents human gastric cancer cells from undergoing apoptosis, and a combination of β- elemene with autophagic inhibitor might thus be a useful therapeutic option for advanced Gastric cancer.Abstract:
Background
β-Elemene, a compound found in an herb used in traditional Chinese medicine, has shown promising anti-cancer effects against a broad spectrum of tumors. The mechanism by which β-elemene kills cells remains unclear. The aim of the present study is to investigate the anti-tumor effect of β-elemene on human gastric cancer cells and the molecular mechanism involved.read more
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