Ya-Chen Lin

TL;DR: Data indicate that PD‐ICB patients have elevated network connectivity in the mesocorticolimbic network, and behaviorally, proficient reward‐based learning is related to this enhanced limbic and ventral striatal connectivity.

TL;DR: Fractional anisotropy values that differentiate ET from PD localize primarily to thalamic and visual-related pathways, while diffusivity differences localized to the cerebellar peduncles, which complement recent functional imaging studies in ET.

TL;DR: The hypothesis that compulsive behaviors in PD are associated with reduced ventral and dorsal striatal D2/3 expression, similar to changes in comparable behavioral disorders is supported.

TL;DR: The role of MT in generating NM-related contrast in the LC is highlighted by applying high spatial resolution quantitative MT (qMT) imaging to create parametric maps of the macromolecular content of the LC and surrounding tissues.

TL;DR: It is shown that dopamine agonist administration increases frontal cerebral blood flow, particularly in the pre-supplementary motor area (pre-SMA) and the dorsolateral prefrontal cortex (DLPFC), suggesting that treatments which improve frontal cortical activity could ameliorate motor inhibition deficiency in PD patients.