Yan Yu

TL;DR: The effects of conventional and hypofractionated radiation regimens on the immune system and tumor stroma are summarized and how these interactions may provide therapeutic benefit in combination with targeted therapies are discussed.

TL;DR: The AAPM and GEC-ESTRO recommend that robotic systems should demonstrate a spatial accuracy of seed placement ≤1.0 mm in a phantom, based on the current performance of existing robotic brachytherapy systems and propagation of uncertainties.

TL;DR: The resonant energies in high-Z elements such as gold are sufficiently high to ensure significant penetration in body tissue, and hence the possibility of achieving X-radiation dose reduction commensurate with resonant enhancements for cancer theranostics using high- Z nanoparticles and molecular radiosensitizing agents embedded in malignant tumors is considered.

TL;DR: The dosimetric features of shaped fields using the MLC are comparable to those of alloy shaped fields with the standard SL25 collimator, and quantitative measurements of all beam parameters show good agreement with the design specifications of the manufacturer.

TL;DR: If a minimum peripheral dose is prescribed for a permanent 125I prostate implant, and the implant is planned using an idealized implant having precisely spaced seeds, the prescribed dose will rarely, if ever, be achieved.