Y
Yanru Qin
Researcher at Zhengzhou University
Publications - 62
Citations - 1876
Yanru Qin is an academic researcher from Zhengzhou University. The author has contributed to research in topics: Metastasis & Cancer. The author has an hindex of 15, co-authored 60 publications receiving 1014 citations.
Papers
More filters
Journal ArticleDOI
Sintilimab plus a bevacizumab biosimilar (IBI305) versus sorafenib in unresectable hepatocellular carcinoma (ORIENT-32): a randomised, open-label, phase 2-3 study.
Zhenggang Ren,Jianming Xu,Yuxian Bai,Aibing Xu,Shundong Cang,Chengyou Du,Qiu Li,Yinying Lu,Yajin Chen,Yabing Guo,Zhendong Chen,Baorui Liu,Weidong Jia,Jian Wu,Junye Wang,Guoliang Shao,Bixiang Zhang,Yunfeng Shan,Zhiqiang Meng,Jianbing Wu,Shanzhi Gu,Wei Yang,Chao Liu,Xuetao Shi,Zhenyuan Gao,Tao Yin,Jiuwei Cui,Ming Huang,Baocai Xing,Yilei Mao,Gao-Jun Teng,Yanru Qin,Jinhai Wang,Feng Xia,Guowen Yin,Yong Yang,Mingxia Chen,Yan Wang,Hui Zhou,Jia Fan +39 more
TL;DR: The phase 2-3 ORIENT-32 study as discussed by the authors compared sintilimab (a PD-1 inhibitor) plus IBI305, a bevacizumab biosimilar, versus sorafenib as a first-line treatment for unresectable HBV-associated hepatocellular carcinoma.
Journal ArticleDOI
MicroRNA-377 suppresses initiation and progression of esophageal cancer by inhibiting CD133 and VEGF.
B. Li,Wenyan Xu,Wenyan Xu,Wenyan Xu,L. Han,L. Han,K. T. Chan,Sai Wah Tsao,N. P.Y. Lee,Simon Law,L. Y. Xu,E. M. Li,Kwok Wah Chan,Yanru Qin,Xin Yuan Guan,Qing-Yu He,Annie L.M. Cheung,Annie L.M. Cheung +17 more
TL;DR: It is established that miR-377 plays a functional and significant role in suppressing tumor initiation and progression, and may represent a promising non-invasive diagnostic and prognostic biomarker and therapeutic strategy for patients with ESCC.
Journal ArticleDOI
Toripalimab plus chemotherapy in treatment-naïve, advanced esophageal squamous cell carcinoma (JUPITER-06): A multi-center phase 3 trial.
Zi-Xian Wang,Chengxu Cui,Jun Yao,Yanqiao Zhang,Mengxia Li,Jifeng Feng,Shujun Wang,Yun Fan,Jian Hua Shi,Lizhi Zhang,Lin Shen,Yongqian Shu,Cailian Wang,Tian-yang Dai,Teng Mao,Long Chen,Zengqing Guo,Bo Liu,Hongming Pan,Shundong Cang,Yi Jiang,Junye Wang,Min Ye,Zhendong Chen,Da Jiang,Qin Lin,Wei Ren,Junsheng Wang,Lin Wu,Yong Xu,Zhanhui Miao,Meili Sun,Conghua Xie,Ying Liu,Qifeng Wang,Lina Zhao,Canhong Huang,Ke Jiang,Kunyu Yang,Dao-Rui Li,Yunpeng Liu,Zhitu Zhu,Ri Shu Chen,Liqun Jia,Wei Liu,Wangjun Liao,Hong-Xu Liu,Dai-Yuan Ma,Jie Ma,Yanru Qin,Zhi-xiang Shi,Qichun Wei,Ke Xiao,Yan Zhang,Ying Zhang,Xin Chen,Guanghai Dai,Jianxing He,Junhe Li,Guanghui Li,Yong Li,Zhihua Liu,Xianglin Yuan,Junping Zhang,Zhichao Fu,Yifu He,Fang Ju,Zheng Liu,Peng Tang,Tie-Jun Wang,Weibo Wang,Jing Zhang,Xianming Luo,Xiongwen Tang,Rena J. May,Hui Feng,Sheng Yao,Patricia Keegan,Rui-Hua Xu,Feng Wang +79 more
TL;DR: Toripalimab plus TP significantly improved progression-free survival (PFS) and overall survival (OS) in patients with treatment-naïve, advanced esophageal squamous cell carcinoma (ESCC) with a manageable safety profile as mentioned in this paper .
Journal ArticleDOI
MicroRNA-9 promotes tumor metastasis via repressing E-cadherin in esophageal squamous cell carcinoma.
Ye Song,Jiangchao Li,Ying Hui Zhu,Y Dai,Tingting Zeng,Lulu Liu,Jianbiao Li,Hong Bo Wang,Yanru Qin,Mu Sheng Zeng,Xin Yuan Guan,Yan Li +11 more
TL;DR: It is demonstrated that miR-9 plays an important role in ESCC metastasis by activating β-catenin pathway and inducing EMT via targeting E-cadherin and serving as a new independent prognostic marker and/or as a novel potential therapeutic target for ESCC.
Journal ArticleDOI
Characterization of Tumor Suppressive Function of cornulin in Esophageal Squamous Cell Carcinoma
Kai Chen,Yan Li,Y Dai,Jiangchao Li,Jiangchao Li,Yanru Qin,Ying Hui Zhu,Tingting Zeng,Xiaojiao Ban,Li Fu,Li Fu,Xin Yuan Guan +11 more
TL;DR: Wang et al. as mentioned in this paper investigated the role of cornulin gene in esophageal squamous cell carcinoma (ESCC) development and found that CRNN was frequently downregulated in primary ESCCs in both mRNA level (26/56, 46.4%) and protein level (137/249, 55%).