Yarong Song

TL;DR: It is reported that ANRIL possibly serves as an oncogene in bladder cancer and regulates bladder cancer cell proliferation and apoptosis through the intrinsic apoptosis pathway.

TL;DR: It is established that AMPK/GSK3b/ b‐catenin cascade‐triggered CEMIP overexpression might promote migration and invasion in anoikis‐resistant PCa cells by enhancing PDK4‐associated metabolic reprogramming, which may provide a novel, promising therapeutic target for the treatment of advanced PCa.

TL;DR: The data showed that OA inhibited cell viability and proliferation, and promoted cell apoptosis and G0/G1 phase cell cycle arrest in prostate cancer PC-3, DU145, and LNCaP cells, in a dose-dependent manner and provided experimental evidence for the use of OA as an adjuvant agent for prostate cancer patients.

TL;DR: It was demonstrated by immunohistochemical analysis that both BDNF and TrkB were overexpressed in PCa tissues and elevated TrkB expression was tightly related with lymph node metastasis and advanced stage of PCa.

TL;DR: It is demonstrated that T4 promoted migration and depressed detachment-induced apoptosis in anoikis-resistant prostate cancer cells while tetraiodothyroacetic acid (tetrac), a competitive antagonist of T4 at integrin αvβ3, reversed T4 induced effects through diminishing expressions of XIAP, MMP-2, VEGF together with inhibited activity of MAPK/ERK pathway.