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Yi-Ping Li
Researcher at University of Texas Health Science Center at Houston
Publications - 55
Citations - 6092
Yi-Ping Li is an academic researcher from University of Texas Health Science Center at Houston. The author has contributed to research in topics: Myogenesis & Skeletal muscle. The author has an hindex of 34, co-authored 48 publications receiving 5534 citations. Previous affiliations of Yi-Ping Li include University of Texas at Austin & University of Texas Health Science Center at San Antonio.
Papers
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Journal ArticleDOI
TNF-α acts via p38 MAPK to stimulate expression of the ubiquitin ligase atrogin1/MAFbx in skeletal muscle
Yi-Ping Li,Yuling Chen,Joseph John,Jennifer S. Moylan,Bingwen Jin,Douglas L. Mann,Michael B. Reid +6 more
TL;DR: The data suggest that TNF‐α acts via p38 to increase atrogin1/MAFbx gene expression in skeletal muscle, which is similar to what was found with H2O2.
Journal ArticleDOI
Skeletal muscle myocytes undergo protein loss and reactive oxygen-mediated NF-κB activation in response to tumor necrosis factor α
TL;DR: TNF-α treatment of differentiated myotubes stimulated time- and concentration-dependent reductions in total protein content and loss of adult myosin heavy chain (MHCf) content; these changes were evident at low TNF- α concentrations that did not alter muscle DNA content and were not associated with a decrease in MHCf synthesis.
Journal ArticleDOI
NF-κB mediates the protein loss induced by TNF-α in differentiated skeletal muscle myotubes
Yi-Ping Li,Micheal B. Reid +1 more
TL;DR: It is shown that NF-κB regulates the transcription of a variety of genes involved in immune responses, cell growth, and cell death and its role in muscle biology is poorly understood.
Journal ArticleDOI
Tumor necrosis factor-α and muscle wasting: a cellular perspective
Michael B. Reid,Yi-Ping Li +1 more
TL;DR: This commentary outlines the current understanding of T NF-α effects on skeletal muscle and the mechanism of TNF-α action.
Commentary Tumor necrosis factor-α and muscle wasting: a cellular perspective
Michael B Reid,Yi-Ping Li +1 more
TL;DR: This article showed that TNF-α disrupts the differentiation process and can promote catabolism in mature cells, and the latter response appears to be mediated by reactive oxygen species and nuclear factor-κB which upregulate ubiquitin/proteasome activity.