Yifei Sun

TL;DR: Findings suggest that modulating lncRNA expression is an important mechanism for risk-associated SNPs in promoting prostate transformation.

TL;DR: This work suggests that RBM5-AS1 activity is critical for the functional enablement of colon cancer stem-like cells, and defines the mechanism of action of R BM5- AS1 in the WNT pathway via physical interactions with β-catenin, helping organize transcriptional complexes that sustain colon CIC function.

TL;DR: A novel mechanism through which the PRMT5/WDR77 complex maintains the balance between splicing and mRNA stability through methylation of ZNF326 is identified.

TL;DR: It is shown that wild-type THAP1 regulates embryonic stem cell (ESC) potential, survival, and proliferation, and ChIP-Seq reveals that these activities are likely due in part to indirect regulation of gene expression.

TL;DR: Lee et al. as discussed by the authors used full-length sc/single-nuclei (sn) RNA-Seq technology to analyze WAT and SVF in humans and found that WAT snRNA-seq provided coverage of major cell types, identified three distinct adipocyte clusters, and was capable of tracking adipocyte differentiation with pseudotime.