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Yilian Cheng
Researcher at Peking Union Medical College
Publications - 3
Citations - 185
Yilian Cheng is an academic researcher from Peking Union Medical College. The author has contributed to research in topics: Gene & Genome-wide association study. The author has an hindex of 2, co-authored 2 publications receiving 150 citations.
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Journal ArticleDOI
Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma
Yuhong Chen,Ying Lin,Eranga N. Vithana,Liyun Jia,Xianbo Zuo,Tien Yin Wong,Li Jia Chen,Xianjun Zhu,Pancy O. S. Tam,Bo Gong,Shaohong Qian,Zheng Li,Xiaoqi Liu,Baskaran Mani,Qian Luo,Celeste Guzman,Christopher Kai-Shun Leung,Xiaobo Li,Wenjun Cao,Quanyao Yang,Clement C Y Tham,Yilian Cheng,Xuejun Zhang,Ningli Wang,Tin Aung,Chiea Chuen Khor,Chi Pui Pang,Xinghuai Sun,Zhenglin Yang +28 more
TL;DR: Both ABCA1 and PMM2 are expressed in the trabecular meshwork, optic nerve and other ocular tissues, a finding consistent with it having a role in the development of glaucoma.
Journal ArticleDOI
Genome-wide analysis identified 17 new loci influencing intraocular pressure in Chinese population
Lulin Huang,Lulin Huang,Yuhong Chen,Ying Lin,Ying Lin,Pancy O. S. Tam,Yilian Cheng,Yi Shi,Bo Gong,Fang Lu,Jialiang Yang,Haixin Wang,Yi Yin,Yong Cao,Dan Jiang,Ling Zhong,Bai Xue,Jing Wang,Fang Hao,Dean-Yao Lee,Chi Pui Pang,Xinghuai Sun,Zhenglin Yang,Zhenglin Yang +23 more
TL;DR: The genetic loci identified in this study not only increase the understanding of the genes involved in intraocular pressure but also provide important genetic markers to improve future genetic screening and drug discovery for intraocular Pressure disorders.
Journal ArticleDOI
Cholesterol homeostasis regulated by ABCA1 is critical for retinal ganglion cell survival
Jialiang Yang,Yurong Chen,Tongdan Zou,Bai Xue,Fang Yang,Xiangzhou Wang,Yibo Huo,Boyun Yan,Yuxia Xu,Shiyu He,Yi-qiong Yin,Jing Wang,Xiong Zhu,Lin Zhang,Zhengfu Tai,Ping Shuai,Man Yu,Qian Luo,Yilian Cheng,Bo Gong,Xianjun Zhu,Jing Zhang,Xinghuai Sun,Ying-yi Lin,Houbin Zhang,Zhenglin Yang +25 more
TL;DR: It is shown that lower ABCA1 expression and lower HDL are risk factors for POAG, and statin use as a preventive treatment forPOAG associated with lower ABCa1 expression is established.