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Xuejun Zhang
Researcher at Anhui Medical University
Publications - 235
Citations - 6132
Xuejun Zhang is an academic researcher from Anhui Medical University. The author has contributed to research in topics: Genome-wide association study & Single-nucleotide polymorphism. The author has an hindex of 35, co-authored 226 publications receiving 4788 citations. Previous affiliations of Xuejun Zhang include Harvard University & Beth Israel Deaconess Medical Center.
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Journal ArticleDOI
Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases A Mendelian Randomization Study
Philip C Haycock,Stephen Burgess,Aayah Nounu,Jie Zheng,G N Okoli,Jack Bowden,Kaitlin H Wade,Nicholas J. Timpson,David M. Evans,Peter Willeit,Abraham Aviv,Tom R. Gaunt,Gibran Hemani,Massimo Mangino,Hayley P Ellis,Kathreena M Kurian,Karen A. Pooley,Rosalind A. Eeles,Jeffrey E. Lee,Shenying Fang,Wei V. Chen,Matthew Law,Lisa Bowdler,Mark M. Iles,Qiong Yang,Bradford B. Worrall,Hugh S. Markus,Rayjean J. Hung,Christopher I. Amos,Amanda B. Spurdle,Deborah J. Thompson,Tracy A. O'Mara,Brian M. Wolpin,Laufey T. Amundadottir,Rachael Z. Stolzenberg-Solomon,Antonia Trichopoulou,N. Charlotte Onland-Moret,Eiliv Lund,Eric J. Duell,Federico Canzian,Gianluca Severi,Kim Overvad,Marc J. Gunter,Rosario Tumino,Ulrika Svenson,Andre M. van Rij,Annette F. Baas,Matthew J. Bown,Nilesh J. Samani,Femke N G van t'Hof,Gerard Tromp,Gregory T. Jones,Helena Kuivaniemi,James R. Elmore,Mattias Johansson,James McKay,Ghislaine Scelo,Robert Carreras-Torres,Valerie Gaborieau,Paul Brennan,Paige M. Bracci,Rachel E. Neale,Sara H. Olson,Steven Gallinger,Donghui Li,Gloria M. Petersen,Harvey A. Risch,Alison P. Klein,Jiali Han,Christian C. Abnet,Neal D. Freedman,Philip R. Taylor,John M. Maris,Katja K.H. Aben,Lambertus A. Kiemeney,Sita H. Vermeulen,John K. Wiencke,Kyle M. Walsh,Margaret Wrensch,Terri Rice,Clare Turnbull,Kevin Litchfield,Lavinia Paternoster,Marie Standl,Gonçalo R. Abecasis,John Paul SanGiovanni,Yong Li,Vladan Mijatovic,Yadav Sapkota,Siew-Kee Low,Krina T. Zondervan,Grant W. Montgomery,Dale R. Nyholt,David A. van Heel,Karen A. Hunt,Dan E. Arking,Foram N. Ashar,Nona Sotoodehnia,Daniel Woo,Jonathan Rosand,Mary E. Comeau,W. Mark Brown,Edwin K. Silverman,John E. Hokanson,Michael H. Cho,Jennie Hui,Manuel A. R. Ferreira,Philip J. Thompson,Alanna C. Morrison,Janine F. Felix,Nicholas L. Smith,Angela M. Christiano,Lynn Petukhova,Regina C. Betz,Xing Fan,Xuejun Zhang,Caihong Zhu,Carl D. Langefeld,Susan D. Thompson,Feijie Wang,Xu Lin,David A. Schwartz,Tasha E. Fingerlin,Jerome I. Rotter,Mary Frances Cotch,Richard A. Jensen,Matthias Munz,Henrik Dommisch,Arne S. Schaefer,Fang Han,Hanna Ollila,Ryan P. Hillary,Omar M. E. Albagha,Stuart H. Ralston,Chenjie Zeng,Wei Zheng,Xiao-Ou Shu,André Reis,Steffen Uebe,Ulrike Hüffmeier,Yoshiya Kawamura,Takeshi Otowa,Tsukasa Sasaki,Martin L. Hibberd,Sonia Davila,Gang Xie,Katherine A. Siminovitch,Jin-Xin Bei,Yi Xin Zeng,Asta Försti,Bowang Chen,Stefano Landi,Andre Franke,Annegret Fischer,David Ellinghaus,Carlos Flores,Imre Noth,Shwu-Fan Ma,Jia Nee Foo,Jianjun Liu,Jong-Won Kim,David G. Cox,Olivier Delattre,Olivier Mirabeau,Christine F. Skibola,Clara S. Tang,Merce Garcia-Barcelo,Kai-Ping Chang,Wen-Hui Su,Yu-Sun Chang,Nicholas G. Martin,Scott D. Gordon,Tracey D. Wade,Chaeyoung Lee,Michiaki Kubo,Pei-Chieng Cha,Yusuke Nakamura,Daniel Levy,Masayuki Kimura,Shih-Jen Hwang,Steven C. Hunt,Tim D. Spector,Nicole Soranzo,Ani Manichaikul,R. Graham Barr,Bratati Kahali,Elizabeth K. Speliotes,Laura M. Yerges-Armstrong,Ching-Yu Cheng,Jost B. Jonas,Tien Yin Wong,Isabella Fogh,Kuang Lin,John Powell,Kenneth Rice,Caroline L Relton,Richard M. Martin,George Davey Smith +197 more
TL;DR: It is likely that longer telomeres increase risk for several cancers but reduce risk for some non-neoplastic diseases, including cardiovascular diseases, as well as single nucleotide polymorphisms (SNPs) that are strongly associated with telomere length in the general population.
Journal ArticleDOI
Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54.
Li-Dong Wang,Fu You Zhou,Xue Min Li,Liangdan Sun,Xin Song,Jin Yan,Jiang Man Li,Guo Qiang Kong,Hong Qi,Juan Cui,Lian Qun Zhang,Jie Zhi Yang,Ji Lin Li,Xing Chuan Li,Jing-Li Ren,Zhi Cai Liu,Wen Jun Gao,Ling Yuan,Wu Wei,Yan Rui Zhang,Wei Peng Wang,Ilyar Sheyhidin,Feng Li,Bao Ping Chen,Shu Wei Ren,Bin Liu,Dan Li,Jian Wei Ku,Zong Min Fan,Sheng Li Zhou,Zhi Gang Guo,Xue Ke Zhao,Na Liu,Yong Hong Ai,Fang Fang Shen,Wen Yan Cui,Shuang Song,Tao Guo,Jing Huang,Chao Yuan,Jia Huang,Yue Wu,Wen Bin Yue,Chang Wei Feng,Hong Lei Li,Yan Wang,Jin Ya Tian,Yue Lu,Yi Yuan,Wen Liang Zhu,Min Liu,Wen Jing Fu,Xia Yang,Han Jing Wang,Suo Li Han,Jie Chen,Min Han,Hai Yan Wang,Peng Zhang,Xiu-Min Li,Jin Cheng Dong,Guo Lan Xing,Ran Wang,Ming Guo,Zhi Wei Chang,Hai Lin Liu,Li Guo,Zhi Qing Yuan,Hai Liu,Qin Lu,Liu Qin Yang,Fu Guo Zhu,Xiu Feng Yang,Xiao Shan Feng,Zhou Wang,Yin Li,She Gan Gao,Qirenwang Qige,Long Tang Bai,Wen Jun Yang,Guang Yan Lei,Zhong Ying Shen,Long Qi Chen,En Min Li,Li Yan Xu,Zhi Yong Wu,Wei Ke Cao,Jian Po Wang,Zhi Qin Bao,Ji Li Chen,Guang Cheng Ding,Xiang Zhuang,Ying Fa Zhou,Hou-Feng Zheng,Zheng Zhang,Xian Bo Zuo,Zi Ming Dong,Dong Mei Fan,Xin He,Jin Wang,Qi Zhou,Qin Xian Zhang,Xin Ying Jiao,Shi Yong Lian,Ai Fang Ji,Xiao Mei Lu,Jin Sheng Wang,Fu Bao Chang,Chang Dong Lu,Zhiguo Chen,Jian Jun Miao,Zeng Lin Fan,Ruo Bai Lin,Tai Jiang Liu,Jin Chang Wei,Qing Peng Kong,Yu Lan,Yu Jing Fan,Fu Sheng Gao,Tian Yun Wang,Dong Xie,Shuqing Chen,Wancai Yang,Jun Yan Hong,Jun Yan Hong,Liang Wang,Song Liang Qiu,Zhi Ming Cai,Xuejun Zhang +128 more
TL;DR: A previously unknown susceptibility locus for ESCC is identified: PLCE1 at 10q23, which might regulate cell growth, differentiation, apoptosis and angiogenesis and has important biological implications for both ESCC and GCA.
Journal ArticleDOI
Genetic susceptibility to SLE: Recent progress from GWAS
TL;DR: This review summarizes the key loci, achieving genome-wide significance, which have been shown to predispose to SLE and may help building the foundation for genetic diagnosis and personalized treatment for patients with SLE in the near future.
Journal ArticleDOI
Corrigendum: Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54
Li-Dong Wang,Zhou Fuyou,Xue-Min Li,Liangdan Sun,Xin Song,Jin Yan,Jiang-Man Li,Guo-Qiang Kong,Hong Qi,Juan Cui,Lian-Qun Zhang,Jie-Zhi Yang,Ji-Lin Li,Xing-Chuan Li,Jing-Li Ren,Zhi-Cai Liu,Wen Jun Gao,Ling Yuan,Wu Wei,Yan-Rui Zhang,Wei Peng Wang,Ilyar Sheyhidin,Feng Li,Bao-Ping Chen,Shu-Wei Ren,Bin Liu,Dan Li,Jian-Wei Ku,Zong-Min Fan,Shengli Zhou,Zhi-Gang Guo,Zhao Xueke,Na Liu,Yong-Hong Ai,Fang-Fang Shen,Wen-Yan Cui,Shuang Song,Tao Guo,Jing Huang,Chao Yuan,Jia Huang,Yue Wu,Wen-Bin Yue,Chang-Wei Feng,Hong-Lei Li,Yan Wang,Jin-Ya Tian,Yue Lu,Yi Yuan,Wen Liang Zhu,Min Liu,Wen-Jing Fu,Xia Yang,Han-Jing Wang,Suo-Li Han,Jie Chen,Min Han,Haiyan Wang,Peng Zhang,Xiu-Min Li,Jin-Cheng Dong,Guo-Lan Xing,Ran Wang,Ming Guo,Zhi-Wei Chang,Hai Lin Liu,Li Guo,Zhi-Qing Yuan,Hai Liu,Qin Lu,Liu Qin Yang,Fu-Guo Zhu,Xiu-Feng Yang,Xiao-Shan Feng,Zhou Wang,Yin Li,She-Gan Gao,Qirenwang Qige,Long-Tang Bai,Wen-Jun Yang,Guang-Yan Lei,Zhong-Ying Shen,Long-Qi Chen,En-Min Li,Li-Yan Xu,Zhi-Yong Wu,Wei-Ke Cao,Jian-Po Wang,Zhi-Qin Bao,Ji-Li Chen,Guang-Cheng Ding,Xiang Zhuang,Ying-Fa Zhou,Hou-Feng Zheng,Zheng Zhang,Xianbo Zuo,Zi-Ming Dong,Dong-Mei Fan,Xin He,Jin Wang,Qi Zhou,Qin-Xian Zhang,Xin-Ying Jiao,Shi-Yong Lian,Ai-Fang Ji,Xiao-Mei Lu,Jin-Sheng Wang,Fu-Bao Chang,Changdong Lu,Zhiguo Chen,Jian-Jun Miao,Zeng-Lin Fan,Ruo-Bai Lin,Tai-Jiang Liu,Jin-Chang Wei,Qing-Peng Kong,Yu Lan,Yu-Jing Fan,Fu-Sheng Gao,Tian-Yun Wang,Dong Xie,Shuqing Chen,Wancai Yang,Jun-Yan Hong,Liang Wang,Song-Liang Qiu,Zhi-Ming Cai,Xuejun Zhang +127 more
TL;DR: The authors now find no evidence to support association with esophageal squamous cell carcinoma susceptibility for rs13042395[T] at 20p13 in their original data, in two independent sets of cases and controls collected in other Chinese populations or in the joint analysis of these three studies.
Journal ArticleDOI
Deep sequencing of the MHC region in the Chinese population contributes to studies of complex disease
Fusheng Zhou,Hongzhi Cao,Xianbo Zuo,Tao Zhang,Xiaoguang Zhang,Xiaomin Liu,Ricong Xu,Gang Chen,Yuanwei Zhang,Xiaodong Zheng,Xin Jin,Jinping Gao,Junpu Mei,Yujun Sheng,Qibin Li,Bo Liang,Juan Shen,Changbing Shen,Hui Jiang,Caihong Zhu,Xing Fan,Fengping Xu,Min Yue,Xianyong Yin,Chen Ye,Cuicui Zhang,Xiao Liu,Liang Yu,Jinghua Wu,Mengyun Chen,Xuehan Zhuang,Lili Tang,Haojing Shao,Longmao Wu,Jian Li,Yu Xu,Yijie Zhang,Suli Zhao,Yu Wang,Ge Li,Hanshi Xu,Lei Zeng,Jianan Wang,Mingzhou Bai,Yanling Chen,Wei Chen,Tian Kang,Yan-Yan Wu,Xun Xu,Zhengwei Zhu,Yong Cui,Zaixing Wang,Chun-Jun Yang,Pei-Guang Wang,Leihong Xiang,Xiang Chen,Anping Zhang,Xinghua Gao,Furen Zhang,Jinhua Xu,Min Zheng,Jie Zheng,Jianzhong Zhang,Xueqing Yu,Yingrui Li,Sen Yang,Huanming Yang,Jian Wang,Jianjun Liu,Lennart Hammarström,Liangdan Sun,Jun Wang,Xuejun Zhang +72 more
TL;DR: The entire 5-Mb MHC region in 20,635 individuals of Han Chinese ancestry is sequenced and a Han-MHC database is constructed that includes both variants and HLA gene typing results of high accuracy to advance understanding of the pathogenesis of these disorders.