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Yiling Yang
Researcher at Huazhong Agricultural University
Publications - 4
Citations - 70
Yiling Yang is an academic researcher from Huazhong Agricultural University. The author has contributed to research in topics: Virus & NSP1. The author has an hindex of 2, co-authored 3 publications receiving 40 citations.
Papers
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Journal ArticleDOI
A conserved region of nonstructural protein 1 from alphacoronaviruses inhibits host gene expression and is critical for viral virulence.
Zhou Shen,Gang Wang,Yiling Yang,Jiale Shi,Liurong Fang,Fang Li,Shaobo Xiao,Zhen F. Fu,Zhen F. Fu,Guiqing Peng +9 more
TL;DR: It is demonstrated that alphacoronavirus nsp1 is an essential virulence determinant, providing a potential paradigm for the development of a new attenuated vaccine based on modified nSp1.
Journal ArticleDOI
Structural and Biological Basis of Alphacoronavirus nsp1 Associated with Host Proliferation and Immune Evasion.
Zhou Shen,Yiling Yang,Siqi Yang,Guangxu Zhang,Shaobo Xiao,Zhen F. Fu,Zhen F. Fu,Guiqing Peng +7 more
TL;DR: In this article, the authors reported the 2.1-length crystal structure of nsp1 in emerging porcine SADS-CoV and the 1.8-length structure of NSP1 in the highly lethal cat FIPV.
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Establishment of Full-Length cDNA Clones and an Efficient Oral Infection Model for Feline Coronavirus in Cats.
Gang Wang,Guangli Hu,Rui Liang,Jiale Shi,Xiuxiu Qiu,Yiling Yang,Zhe Jiao,Yixi Chen,Zhou Shen,Mengxia Li,Yuejun Shi,Junfu Mao,Guiqing Peng +12 more
TL;DR: Wang et al. as discussed by the authors constructed a field type I FIPV full-length cDNA clone, pBAC-QS, corresponding to the isolated FipV QS, and established and rescued a recombinant virus, designated rQS-79.
Journal ArticleDOI
mLST8 is essential for coronavirus replication and regulates its replication through the mTORC1 pathway
Yanan Fu,Zhen F. Fu,Zhelin Su,Lisha Li,Yiling Yang,Yubei Tan,Yixin Xiang,Yuejun Shi,Shengsong Xie,Limeng Sun,Guiqing Peng +10 more
TL;DR: In this paper , a host factor, mammalian lethal with sec-13 protein 8 (mLST8), was identified as a host regulator of CoV replication, which can facilitate the development of broad-spectrum antiviral drugs.