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Yimin Zhu
Researcher at Chinese Academy of Sciences
Publications - 54
Citations - 1035
Yimin Zhu is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Chemistry & Engineering. The author has an hindex of 16, co-authored 30 publications receiving 790 citations. Previous affiliations of Yimin Zhu include National University of Singapore.
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Role of surface charge and oxidative stress in cytotoxicity and genotoxicity of graphene oxide towards human lung fibroblast cells
TL;DR: The cytotoxicity and genotoxicity of GO to human lung fibroblast (HLF) cells have been assessed with methyl thiazolyl tetrazolium (MTT), sub‐G1 measurement and comet assays, and the mechanism of its toxicity has been explored.
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Inflammation and cancer stem cells.
Sarah Shigdar,Yong Li,Santanu Bhattacharya,Michael O’Connor,Chunwen Pu,Jia Lin,Tao Wang,Dongxi Xiang,Lingxue Kong,Ming Q. Wei,Yimin Zhu,Shu-Feng Zhou,Wei Duan +12 more
TL;DR: Cancer stem cells are becoming recognised as being responsible for metastasis and treatment resistance, and the complex cellular and molecular network that regulates cancer stem cells and the role that inflammation plays in cancer progression are slowly being elucidated.
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Aptamers as Theranostic Agents: Modifications, Serum Stability and Functionalisation
Sarah Shigdar,Joanna Macdonald,Michael O’Connor,Tao Wang,Dongxi Xiang,Hadi Al. Shamaileh,Liang Qiao,Ming Q. Wei,Shu-Feng Zhou,Yimin Zhu,Lingxue Kong,Santanu Bhattacharya,Chun Guang Li,Wei Duan +13 more
TL;DR: The use of modified bases as a means of enhancing serum stability and producing effective therapeutic tools, as well as functionalising these nucleic acids to be used as potential diagnostic agents are discussed.
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Functionalization of upconverted luminescent NaYF4 : Yb/Er nanocrystals by folic acid–chitosan conjugates for targeted lung cancer cell imaging
TL;DR: The surface chemistry and functional design of the upconverted luminescent NaYF4:Yb/Er nanocrystals using biocompatible FA–chitosan conjugates might provide a powerful nanoplatform for the detection and molecular diagnosis of lung cancer.
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Aptamer-guided extracellular vesicle theranostics in oncology
Phuong H-L Tran,Dongxi Xiang,Tuong Ngoc-Gia Nguyen,Thao T D Tran,Qian Chen,Wang Yin,Yumei Zhang,Lingxue Kong,Andrew Duan,Kuisheng Chen,Miomio Sun,Yong Li,Yingchun Hou,Yimin Zhu,Yongchao Ma,Guoqin Jiang,Wei Duan +16 more
TL;DR: A current picture of the research on exosomes and aptamers and their applications in cancer theranostics is provided, highlighting recent advances in their transition from the bench to the clinic.