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Ying Wu Lin
Researcher at University of Illinois at Urbana–Champaign
Publications - 4
Citations - 386
Ying Wu Lin is an academic researcher from University of Illinois at Urbana–Champaign. The author has contributed to research in topics: Heme & Myoglobin. The author has an hindex of 4, co-authored 4 publications receiving 354 citations.
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Journal ArticleDOI
Rational design of a structural and functional nitric oxide reductase
Natasha Yeung,Ying Wu Lin,Yi Gui Gao,Xuan Zhao,Brandy S. Russell,Lanyu Lei,Kyle D. Miner,Howard Robinson,Yi Lu +8 more
TL;DR: A successful, rational design of a structural and functional model of a metalloprotein, nitric oxide reductase (NOR), by introducing three histidines and one glutamate, predicted as ligands in the active site of NOR, into the distal pocket of myoglobin is reported.
Journal ArticleDOI
Roles of glutamates and metal ions in a rationally designed nitric oxide reductase based on myoglobin.
TL;DR: The designed protein offers an excellent model for NOR and demonstrates the power of using designed proteins as a simpler and more well-defined system to address important chemical and biological issues.
Journal ArticleDOI
Introducing a 2-His-1-Glu nonheme iron center into myoglobin confers nitric oxide reductase activity.
TL;DR: A novel protein model of NOR is presented and insights are provided into a newly discovered member of the NOR family, gNOR, which plays crucial roles in NOR activity.
Journal ArticleDOI
Spectroscopic Characterization of Mononitrosyl Complexes in Heme–Nonheme Diiron Centers within the Myoglobin Scaffold (FeBMbs): Relevance to Denitrifying NO Reductase
TL;DR: UV--vis absorption and resonance Raman spectra demonstrate that the first NO molecule binds to the ferrous heme, but while the apoproteins and Cu(I)- or Zn(II)-loaded proteins show characteristic EPR signatures of S = 1/2 six-coordinate heme {FeNO}(7) species that can be observed at liquid nitrogen temperature, the Fe(II-loaded proteins are EPR silent at ≥30 K.