Y
Yinghan Chan
Researcher at International Medical University
Publications - 18
Citations - 274
Yinghan Chan is an academic researcher from International Medical University. The author has contributed to research in topics: Celastrol & Drug delivery. The author has an hindex of 5, co-authored 18 publications receiving 118 citations. Previous affiliations of Yinghan Chan include University of Malaya.
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Journal ArticleDOI
Molecular modulators of celastrol as the keystones for its diverse pharmacological activities
Sin Wi Ng,Yinghan Chan,Dinesh Kumar Chellappan,Thiagarajan Madheswaran,Farrukh Zeeshan,Yik Lung Chan,Trudi Collet,Gaurav Gupta,Brian G. Oliver,Peter A. B. Wark,Nicole G. Hansbro,Alan Hsu,Philip M. Hansbro,Philip M. Hansbro,Kamal Dua,Kamal Dua,Jithendra Panneerselvam +16 more
TL;DR: This review has collated the various research findings related to the molecular modulators responsible for different pharmacological activities shown by celastrol and suggests a new direction in the area of herbal drug discovery and development.
Journal ArticleDOI
Perspectives and advancements in the design of nanomaterials for targeted cancer theranostics.
Yoke Ying Tan,Pui Khee Yap,Griselda Loo Xin Lim,Meenu Mehta,Yinghan Chan,Sin Wi Ng,Deepak N. Kapoor,Poonam Negi,Krishnan Anand,Sachin Kumar Singh,Niraj Kumar Jha,Lay Cheng Lim,Thiagarajan Madheswaran,Saurabh Satija,Gaurav Gupta,Kamal Dua,Kamal Dua,Dinesh Kumar Chellappan +17 more
TL;DR: Theranostics has successfully paved a path to a new era of drug design and development, in which nanomaterials and imaging contribute to a large variety of cancer therapies and provide a promising future in the effective management of various cancers.
Journal ArticleDOI
Celastrol-loaded liquid crystalline nanoparticles as an anti-inflammatory intervention for the treatment of asthma
Yinghan Chan,Sin Wi Ng,Dinesh Kumar Chellappan,Thiagarajan Madheswaran,Farrukh Zeeshan,Pradeep Kumar,Viness Pillay,Gaurav Gupta,Ridhima Wadhwa,Meenu Mehta,Peter A. B. Wark,Alan Hsu,Nicole G. Hansbro,Philip M. Hansbro,Kamal Dua,Jithendra Panneerselvam +15 more
TL;DR: In this paper, the authors formulated celastrol into liquid crystalline nanoparticles (LCNPs) through ultrasonication to enhance its therapeutic efficacy in the treatment of asthma.
Journal ArticleDOI
Emerging therapeutic potential of the iridoid molecule, asperuloside: A snapshot of its underlying molecular mechanisms.
Yinghan Chan,Sin Wi Ng,Joycelin Zhu Xin Tan,Gaurav Gupta,Murtaza M. Tambuwala,Hamid A. Bakshi,Harish Dureja,Kamal Dua,Kamal Dua,Muhammad Ishaq,Vanni Caruso,Dinesh Kumar Chellappan +11 more
TL;DR: This review has attempted to study the various reported mechanisms of asperuloside that form the basis of its wide spectrum of pharmacological activities.
Journal ArticleDOI
Versatility of liquid crystalline nanoparticles in inflammatory lung diseases.
Yinghan Chan,Meenu Mehta,Meenu Mehta,Keshav Raj Paudel,Keshav Raj Paudel,Thiagarajan Madheswaran,Jithendra Panneerselvam,Gaurav Gupta,Qian Peter Su,Philip M. Hansbro,Philip M. Hansbro,Ronan MacLoughlin,Ronan MacLoughlin,Kamal Dua,Kamal Dua,Dinesh Kumar Chellappan +15 more