Yixi Liu

TL;DR: A structure–activity relationship study suggested that the presence of an α,β-unsaturated carbonyl moiety is not essential for potent antimalarial activity.

TL;DR: Three new lignans isolated from Cleistanthus boivinianus showed potent antiproliferative activities against the A2780 ovarian cancer cell line, and compounds 1, 4, and 5 showed potent antimicrobial activity against the HCT-116 human colon carcinoma cell line.

TL;DR: In this paper, a bioassay-directed fractionation of an antiproliferative ethanol extract of the leaves and twigs of Piptocoma antillana (Asteraceae) afforded two new goyazensolide-type sesquiterpene lactones named 5-O-methyl-5-epiisogoyazensolside (1) and 15-O -methylgoyazenolide (2), together with the known compounds 1-oxo-3,10-epoxy-8-(2-

TL;DR: Bioassay-directed fractionation of the leaf and root extracts of the antiproliferative Madagascar plant Stuhlmannia moavi afforded 6-acetyl-5,8-dihydroxy-2-methoxy-7-methyl-1,4-naphthoquinone (stuhlmoavin, 1) as the most active compound, and the structure elucidation of all compounds was based on NMR and mass spectroscopic data.

TL;DR: Bioassay-directed fractionation of an antiproliferative ethanol extract of the roots of Ocotea macrocarpa (Lauraceae) afforded the new butanolide Macrocarpolide A, and the two new secobutanolides macroarpolides B and C, together with the known butanolides linderanolide B (4) and isolinderanolides (5).