Y
Yixing Du
Researcher at Ohio State University
Publications - 20
Citations - 854
Yixing Du is an academic researcher from Ohio State University. The author has contributed to research in topics: Astrocyte & Membrane potential. The author has an hindex of 9, co-authored 16 publications receiving 577 citations. Previous affiliations of Yixing Du include Nanjing Medical University & The Ohio State University Wexner Medical Center.
Papers
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Journal ArticleDOI
Air particulate matter and cardiovascular disease: the epidemiological, biomedical and clinical evidence.
TL;DR: The linking between PM exposure and the occurrence of cardiovascular disease is reviewed and the possible underlying mechanisms for the observed PM induced increases in cardiovascular morbidity and mortality are discussed.
Journal ArticleDOI
Gap junction coupling confers isopotentiality on astrocyte syncytium
Baofeng Ma,Richard Buckalew,Yixing Du,Conrad M. Kiyoshi,Catherine C. Alford,Wei Wang,Dana M. McTigue,John J. Enyeart,David Terman,Min Zhou +9 more
TL;DR: It is demonstrated that the membrane potential of an individual astrocyte in a hippocampal syncytium, but not in a single, freshly isolated cell preparation, can be well‐maintained at quasi-physiological levels when recorded with reduced or K+ free pipette solutions that alter the K+ equilibrium potential to non‐physiological voltages.
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Glial gap junctional communication involvement in hippocampal damage after middle cerebral artery occlusion
Minjie Xie,Chen-Ju Yi,Xiang Luo,Shabei Xu,Zhiyuan Yu,Yingxin Tang,Wenhao Zhu,Yixing Du,Lintao Jia,Qiang Zhang,Qiang Dong,Wenzhen Zhu,Xia Zhang,Bitao Bu,Wei Wang +14 more
TL;DR: The hippocampal damage and its correlation to cognitive defects after exclusively unilateral MCAO and the underlying mechanism for that damage are investigated.
Journal ArticleDOI
Genetic Deletion of TREK-1 or TWIK-1/TREK-1 Potassium Channels does not Alter the Basic Electrophysiological Properties of Mature Hippocampal Astrocytes In Situ.
Yixing Du,Conrad M. Kiyoshi,Qi Wang,Wei Wang,Baofeng Ma,Catherine C. Alford,Shiying Zhong,Qi Wan,Haijun Chen,Eric E. Lloyd,Robert M. Bryan,Min Zhou +11 more
TL;DR: Genetic deletion of TREK-1 alone or together with TWIK-1 produced no obvious alteration in the basic electrophysiological properties of hippocampal astrocytes, and future research focusing on other K+ channels may shed light on this long-standing and important question in astroCyte physiology.
Journal ArticleDOI
Syncytial isopotentiality: A system-wide electrical feature of astrocytic networks in the brain.
Conrad M. Kiyoshi,Yixing Du,Shiying Zhong,Shiying Zhong,Wei Wang,Wei Wang,Anne T. Taylor,Bangyan Xiong,Baofeng Ma,David Terman,Min Zhou +10 more
TL;DR: Using a nonphysiological K+‐free/Na+ electrode solution to depolarize a recorded astrocyte in situ, the existence of syncytial isopotentiality can be revealed: the recorded astracyte's membrane potential remains at a quasi‐physiological level due to strong electrical coupling with neighboringAstrocytes.