Yojiro Ooshima

TL;DR: Adequate designs in NHP are presented for developmental toxicity (embryo-fetal development, pre-postnatal development, enhanced pre- postnatal development), reproductive toxicity (male and female), and juvenile toxicity studies.

TL;DR: This update (version 2) of the Terminology of developmental abnormalities in common laboratory mammals incorporates improvements and enhancements to both content and organization of the terminology, to enable greater flexibility in its application, while maintaining a consistent approach to the description of findings.

TL;DR: The objective of juvenile animal toxicity studies of pharmaceuticals is to obtain safety data, including information on the potential for adverse effects on postnatal growth and development, as well as to assist in identifying postnatal developmental toxicities.

TL;DR: This update (Version 2) of the Terminology of Developmental Abnormalities in Common Laboratory Mammals incorporates improvements and enhancements to both content and organization of the terminology to enable greater flexibility in its application, while maintaining a consistent approach to the description of findings.

TL;DR: This update (Version 2) of the Terminology of Developmental Abnormalities in Common Laboratory Mammals incorporates improvements and enhancements to both content and organization of the terminology, to enable greater flexibility in its application, while maintaining a consistent approach to the description of findings.