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Yolanda R. Smith
Researcher at University of Michigan
Publications - 126
Citations - 6006
Yolanda R. Smith is an academic researcher from University of Michigan. The author has contributed to research in topics: Population & Endometriosis. The author has an hindex of 31, co-authored 117 publications receiving 5398 citations. Previous affiliations of Yolanda R. Smith include Cleveland Clinic & Wayne State University.
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Journal ArticleDOI
COMT val158met Genotype Affects µ-Opioid Neurotransmitter Responses to a Pain Stressor
Jon Kar Zubieta,Mary M. Heitzeg,Yolanda R. Smith,Joshua A. Bueller,Ke Xu,Yanjun Xu,Robert A. Koeppe,Christian S. Stohler,David Goldman +8 more
TL;DR: Individuals homozygous for themet158 allele of the catechol-O-methyltransferase (COMT) polymorphism showed diminished regional μ-opioid system responses to pain compared with heterozygotes, and these effects were accompanied by higher sensory and affective ratings of pain and a more negative internal affective state.
Journal ArticleDOI
Regional mu opioid receptor regulation of sensory and affective dimensions of pain.
Jon Kar Zubieta,Yolanda R. Smith,Joshua A. Bueller,Yanjun Xu,Michael R. Kilbourn,Douglas M. Jewett,Charles R. Meyer,Robert A. Koeppe,Christian S. Stohler +8 more
TL;DR: Sustained pain induced the regional release of endogenous opioids interacting with μ-opioid receptors in a number of cortical and subcortical brain regions, resulting in reductions in the sensory and affective ratings of the pain experience.
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μ-Opioid Receptor-Mediated Antinociceptive Responses Differ in Men and Women
Jon Kar Zubieta,Yolanda R. Smith,Joshua A. Bueller,Yanjun Xu,Michael R. Kilbourn,Douglas M. Jewett,Charles R. Meyer,Robert A. Koeppe,Christian S. Stohler +8 more
TL;DR: It is demonstrated that at matched levels of pain intensity, men and women during their follicular phase differ in the magnitude and direction of response of the μ-opioid system in distinct brain nuclei.
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Pronociceptive and antinociceptive effects of estradiol through endogenous opioid neurotransmission in women.
Yolanda R. Smith,Christian S. Stohler,Thomas E. Nichols,Joshua A. Bueller,Robert A. Koeppe,Jon Kar Zubieta +5 more
TL;DR: A significant role of estrogen in modulating endogenous opioid neurotransmission and associated psychophysical responses to a pain stressor in humans is demonstrated.
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Vulvar lichen sclerosus : pathophysiology and treatment.
Yolanda R. Smith,Hope K. Haefner +1 more
TL;DR: The history, clinical features, pathophysiology, and treatment of lichen sclerosus of the vulva, as well as pregnancy issues and sexual function in patients with this condition are discussed.