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Yonathan Zehavi
Researcher at Bar-Ilan University
Publications - 8
Citations - 230
Yonathan Zehavi is an academic researcher from Bar-Ilan University. The author has contributed to research in topics: Promoter & RNA polymerase II. The author has an hindex of 6, co-authored 7 publications receiving 179 citations.
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Journal ArticleDOI
ElemeNT: a computational tool for detecting core promoter elements.
Anna Sloutskin,Yehuda M. Danino,Yaron Orenstein,Yonathan Zehavi,Tirza Doniger,Ron Shamir,Tamar Juven-Gershon +6 more
TL;DR: The Elements Navigation Tool (ElemeNT) is a user-friendly web-based, interactive tool for prediction and display of putative core promoter elements and their biologically-relevant combinations, and the CORE database summarizes ElemeNT-predicted core promoter Elements near CAGE and RNA-seq-defined Drosophila melanogaster transcription start sites (TSSs).
Journal ArticleDOI
Drosophila TRF2 is a preferential core promoter regulator.
Adi Kedmi,Yonathan Zehavi,Yair Glick,Yaron Orenstein,Diana Ideses,Chaim Wachtel,Tirza Doniger,Hiba Waldman Ben-Asher,Nemone Muster,James Thompson,Scott Anderson,Dorit Avrahami,John R. Yates,Ron Shamir,Doron Gerber,Tamar Juven-Gershon +15 more
TL;DR: This work identified the Drosophila TBP (TATA-box-binding protein)-related factor 2 (TRF2) as an enriched factor in the fractions that support DPE-dependent transcription and shows the importance of the DPE in transcriptional regulation of TRF2 target genes.
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Structural and Dynamics Characterization of the MerR Family Metalloregulator CueR in its Repression and Activation States.
Hila Sameach,Aya Narunsky,Salome Azoulay-Ginsburg,Lada Gevorkyan-Aiapetov,Yonathan Zehavi,Yoni Moskovitz,Tamar Juven-Gershon,Nir Ben-Tal,Sharon Ruthstein +8 more
TL;DR: A detailed structural mechanism underlying CueR's regulation of the transcription process is proposed, which explicitly shows the dependence of CueR activity on copper, thereby revealing the important negative feedback mechanism essential for regulating the intracellular copper concentration.
Journal ArticleDOI
Core promoter functions in the regulation of gene expression of Drosophila dorsal target genes.
TL;DR: Using hybrid enhancer-promoter constructs in Drosophila cells and embryo extracts, it is demonstrated that the core promoter composition is an important determinant of transcriptional activity of Dorsal target genes.
Journal ArticleDOI
TRF2: TRansForming the view of general transcription factors.
TL;DR: This work reviews the recent findings implicating TRF2 as a basal transcription factor in the regulation of diverse biological processes and specialized transcriptional programs and examines its role in TATA box binding and core promoter elements.