Yongjin Sung

TL;DR: The quantitative refractive index map can potentially serve as an intrinsic assay to provide the molecular concentrations without the addition of exogenous agents and also to provide a method for studying the light scattering properties of single cells.

TL;DR: This study uses quantitative phase microscopy to show that mammalian chondrocytes undergo three distinct phases of volume increase, including a phase of massive cell swelling in which the cellular dry mass is significantly diluted, a remarkable mechanism for increasing cell size and regulating growth rate.

TL;DR: A high-speed synthetic aperture microscopy instrument for quantitative phase imaging of live biological cells is presented and artifacts from diffraction that are typically present in coherent imaging are significantly suppressed, and lateral resolution of phase imaging is improved.

TL;DR: In this paper, a no-moving parts approach was proposed to provide 3D refractive index maps of biological samples continuously flowing in a microfluidic channel, using line illumination and off-axis digital holography to record the angular spectra of light scattered from flowing samples at high speed.

TL;DR: A regularized tomographic phase microscope (RTPM) is developed enabling accurate refractive index imaging of organelles inside intact cells, and the mass of chromosomes in intact living cells is quantified, and chromosomal imaging using a dual-wavelength RTPM is demonstrated, which shows its potential to determine the molecular composition of cellular organelle in live cells.