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Yongjing Zhang
Researcher at Xi'an Jiaotong University
Publications - 40
Citations - 614
Yongjing Zhang is an academic researcher from Xi'an Jiaotong University. The author has contributed to research in topics: Degranulation & Mast cell. The author has an hindex of 8, co-authored 35 publications receiving 311 citations.
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Journal ArticleDOI
Research on antioxidant effects and estrogenic effect of formononetin from Trifolium pratense (red clover).
TL;DR: The intake of formononetin increased the uterine weight of the mice significantly as well as the content of SOD, GSH-Px, CAT, and reduced MDA in body and the estrogenic effect was not dosage-related.
Journal ArticleDOI
Chloroquine and hydroxychloroquine as ACE2 blockers to inhibit viropexis of 2019-nCoV Spike pseudotyped virus.
Nan Wang,Shengli Han,Rui Liu,Liesu Meng,Huaizhen He,Yongjing Zhang,Cheng Wang,Yanni Lv,Jue Wang,Xiaowei Li,Yuanyuan Ding,Jia Fu,Yajing Hou,Lu Wen,Weina Ma,Yingzhuan Zhan,Bingling Dai,Jie Zhang,Xiaoyan Pan,Shiling Hu,Jiapan Gao,Qianqian Jia,Liyang Zhang,Shuai Ge,Saisai Wang,Peida Liang,Tian Hu,Jiayu Lu,Xiangjun Wang,Huaxin Zhou,Wenjing Ta,Yuejin Wang,Shemin Lu,Langchong He +33 more
TL;DR: This study investigates whether CQ and HCQ could be ACE2 blockers and used to inhibit 2019-nCoV virus infection and shows that HCQ is slightly more toxic to ACE2h cells than CQ.
Journal ArticleDOI
Mivacurium induce mast cell activation and pseudo-allergic reactions via MAS-related G protein coupled receptor-X2.
Delu Che,Jue Wang,Yuanyuan Ding,Rui Liu,Jiao Cao,Yongjing Zhang,Yajing Hou,Hongli An,Zijun Gao,Tao Zhang +9 more
TL;DR: The targeting of MRGPRX2 can potentially block mivacurium-induced adverse drug effects, particularly pseudo-allergic reactions, which may present a serious threat to the patient's life, particularly in children.
Journal ArticleDOI
Quercetin as a Lyn kinase inhibitor inhibits IgE-mediated allergic conjunctivitis.
Yuanyuan Ding,Chaomei Li,Yongjing Zhang,Pengyu Ma,Tingting Zhao,Delu Che,Jiao Cao,Jue Wang,Rui Liu,Tao Zhang,Langchong He +10 more
TL;DR: The use of quercetin for the treatment of allergic conjunctivitis is illustrated, which might act through its ability to inhibit Lyn/PLCγ/IP3R-Ca2+, Lyn/ERK1/2, and Lyn/NF-κB signaling.
Journal ArticleDOI
Cisatracurium induces mast cell activation and pseudo-allergic reactions via MRGPRX2.
Delu Che,Liu Rui,Jiao Cao,Jue Wang,Yongjing Zhang,Yuanyuan Ding,Tingting Zhao,Pengyu Ma,Hongli An,Zijun Gao,Tao Zhang +10 more
TL;DR: The MRGPRX2‐related pseudo‐allergic reactions induced by cisatracurium were investigated using hindpaw swelling and extravasation assays in vivo and mast cell degranulation assays and it was found that strategies targeting MRG PRX2 might potentially block cisatacurium‐induced pseudo‐ allergic reactions.