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Shemin Lu

Researcher at Xi'an Jiaotong University

Publications -  168
Citations -  5476

Shemin Lu is an academic researcher from Xi'an Jiaotong University. The author has contributed to research in topics: Arthritis & Inflammation. The author has an hindex of 31, co-authored 143 publications receiving 4332 citations. Previous affiliations of Shemin Lu include Lund University & Chinese Ministry of Education.

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Molecular immune pathogenesis and diagnosis of COVID-19.

Xiaowei Li, +9 more
- 05 Mar 2020 - 
TL;DR: A brief introduction of the general features of SARS-CoV-2 is provided and current knowledge of molecular immune pathogenesis, diagnosis and treatment of COVID-19 is discussed, which may be helpful in offering novel insights and potential therapeutic targets for combating the SARS/MERS/CoV infection.
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Positional identification of Ncf1 as a gene that regulates arthritis severity in rats.

Peter Olofsson, +5 more
- 01 Jan 2003 - 
TL;DR: It is found that a naturally occurring polymorphism of Ncf1 (encoding neutrophil cytosolic factor 1, a component of the NADPH oxidase complex) regulates arthritis severity and is associated with a new autoimmune mechanism leading to severe destructive arthritis, notably similar to rheumatoid arthritis in humans.
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Arthritis induced in rats with non-immunogenic adjuvants as models for rheumatoid arthritis

Rikard Holmdahl, +7 more
- 01 Dec 2001 - 
TL;DR: In this article, the authors proposed a disease-oriented genetic approach to unravel the mechanisms behind adjuvant-induced rheumatoid arthritis in rats, and found several loci that control onset of arthritis, severity and chronicity of the disease.
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Reduced apoptosis correlates with enhanced autophagy in synovial tissues of rheumatoid arthritis

Ke Xu, +5 more
- 01 Feb 2013 - 
TL;DR: The impaired apoptosis in RA synovium might result from increased autophagy, which in turn could be due to the deregulation of miRNA-30a.
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A novel long noncoding RNA Lnc-HC binds hnRNPA2B1 to regulate expressions of Cyp7a1 and Abca1 in hepatocytic cholesterol metabolism.

Xi Lan, +27 more
- 01 Jul 2016 - 
TL;DR: A novel lncRNA named lnc‐HC negatively regulating cholesterol metabolism within hepatocytes through physical interaction with hnRNPA2B1 and is defined as a novel line of evidence by which lncRNAs modulate the metabolic system at the post‐transcriptional level.