Yongli Chen

TL;DR: Various mechanisms of controlled drug delivery using polymeric MNs, including new strategies, applications, and their future outlook are summarized and evaluated.

TL;DR: This on chip drug screening study is the first to address the drug susceptibility testing and the offline detailed drug signaling pathway analysis combination on one system, which is crucial for drug discovery and development.

TL;DR: New properties ofissolvable polymeric microneedle fabrication improve their efficacy of transdermal drug delivery and ease of use, enhance their capability of drug control release, enlarge the scope of the polymers that can be used for DPMN fabrication, prevent microbial contamination during the storage and transportation, and reduce infection risk in clinical applications.

TL;DR: An in vitro breast tumor model on a chip, composed of a microvessel wall, the extracellular matrix (ECM) and uniformly sized multicellular tumor spheroids, enables evaluation of dynamic transport behavior and in situ cytotoxicity evaluation in one system.

TL;DR: Mimicking the features of octopuses, a device termed a "NanoOctopus" was developed for cancer cell isolation in whole blood that consists of long multimerized aptamer DNA strands, or tentacle DNA, immobilized on magnetic microparticle surfaces.