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Yoon-Keun Kim
Researcher at Pohang University of Science and Technology
Publications - 147
Citations - 9695
Yoon-Keun Kim is an academic researcher from Pohang University of Science and Technology. The author has contributed to research in topics: Microvesicles & Inflammation. The author has an hindex of 45, co-authored 146 publications receiving 7782 citations. Previous affiliations of Yoon-Keun Kim include New Generation University College.
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Journal ArticleDOI
Bioinspired Exosome-Mimetic Nanovesicles for Targeted Delivery of Chemotherapeutics to Malignant Tumors
Su Chul Jang,Oh Youn Kim,Chang Min Yoon,Dong-Sic Choi,Tae-Young Roh,Jaesung Park,Jonas Nilsson,Jan Lötvall,Yoon-Keun Kim,Yong Song Gho +9 more
TL;DR: Bioinspired exosome-mimetic nanovesicles that deliver chemotherapeutics to the tumor tissue after systemic administration and removal of the plasma membrane proteins by trypsinization eliminated the therapeutic effects of the nanovesicle both in vitro and in vivo are suggested.
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Gram-positive bacteria produce membrane vesicles: proteomics-based characterization of Staphylococcus aureus-derived membrane vesicles.
Eun Young Lee,Do Young Choi,Dae-Kyum Kim,Jung-Wook Kim,Jung Ok Park,Sungjee Kim,Sang-Hyun Kim,Dominic M. Desiderio,Yoon-Keun Kim,Kwang Pyo Kim,Yong Song Gho +10 more
TL;DR: It is found for the first time that Gram‐positive bacteria naturally produce MVs into the extracellular milieu and these observations suggest that the secretion of MVs is an evolutionally conserved, universal process that occurs from simple organisms to complex multicellular organisms.
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Proteomics, transcriptomics and lipidomics of exosomes and ectosomes
TL;DR: Recent advances in the biology, function, and diagnostic potential of vesicle‐specific components of extracellular vesicles are summarized.
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EVpedia: An integrated database of high-throughput data for systemic analyses of extracellular vesicles
Dae-Kyum Kim,Byeongsoo Kang,Oh Youn Kim,Dong-Sic Choi,Jaewook Lee,Sae Rom Kim,Gyeongyun Go,Yae Jin Yoon,Ji-Hyun Kim,Su Chul Jang,Kyong-Su Park,Eun Jeong Choi,Kwang Pyo Kim,Dominic M. Desiderio,Yoon-Keun Kim,Jan Lötvall,Daehee Hwang,Yong Song Gho +17 more
TL;DR: Evolpedia is presented, which is an integrated database of high-throughput datasets from prokaryotic and eukaryotic extracellular vesicles that might serve as a fundamental repository to stimulate the advancement of extrace cellular vesicle studies and to elucidate the novel functions of these complexextracellular organelles.
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Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells
Bok Sil Hong,Ji-Hoon Cho,Hyun-Jung Kim,Eun-Jeong Choi,Sangchul Rho,Jongmin Kim,Ji-Hyun Kim,Dong-Sic Choi,Yoon-Keun Kim,Daehee Hwang,Yong Song Gho +10 more
TL;DR: This study demonstrates that CRC cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells, suggesting that microvesicle of cancer cells can be involved in tumor growth and metastasis by facilitating angiogenesis-related processes.