Y
Yorihiro Nishimura
Researcher at National Institutes of Health
Publications - 36
Citations - 1933
Yorihiro Nishimura is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Viral replication & Enterovirus 71. The author has an hindex of 21, co-authored 35 publications receiving 1767 citations. Previous affiliations of Yorihiro Nishimura include Children's Hospital of Philadelphia & University of Tokyo.
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Journal ArticleDOI
Human P-selectin glycoprotein ligand-1 is a functional receptor for enterovirus 71
Yorihiro Nishimura,Masayuki Shimojima,Yoshio Tano,Tatsuo Miyamura,Takaji Wakita,Hiroyuki Shimizu +5 more
TL;DR: Nishimura et al. as mentioned in this paper identified two different receptors for EV71, P-selectin glycoprotein ligand-1 ((PSGL-1) and scavenger receptor class B, member 2 (SCARB2).
Journal ArticleDOI
Hepatitis C virus RNA replication is regulated by FKBP8 and Hsp90.
Toru Okamoto,Yorihiro Nishimura,Tohru Ichimura,Kensuke Suzuki,Tatsuo Miyamura,Tetsuro Suzuki,Kohji Moriishi,Yoshiharu Matsuura +7 more
TL;DR: It is shown that NS5A specifically interacts with FKBP8, a member of the FK506‐binding protein family, but not with other homologous immunophilins.
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Human VAP-B Is Involved in Hepatitis C Virus Replication through Interaction with NS5A and NS5B
Itsuki Hamamoto,Yorihiro Nishimura,Yorihiro Nishimura,Toru Okamoto,Hideki Aizaki,Hideki Aizaki,Minyi Liu,Yoshio Mori,Takayuki Abe,Tetsuro Suzuki,Michael M. C. Lai,Tatsuo Miyamura,Kohji Moriishi,Yoshiharu Matsuura +13 more
TL;DR: VAP-B, in addition to VAP-A, plays an important role in the replication of the HCV genome, according to immunoprecipitation and mutation analyses.
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Multiple Independent Emergences of Type 2 Vaccine-Derived Polioviruses during a Large Outbreak in northern Nigeria
Cara C. Burns,Jing Shaw,Jaume Jorba,David Bukbuk,F.D. Adu,N. Gumede,Muhammed A. Pate,Emmanuel Abanida,Alex Gasasira,Jane Iber,Qi Chen,Annelet Vincent,Paul Chenoweth,Elizabeth Henderson,Kathleen Wannemuehler,Asif Naeem,Rifqiyah Nur Umami,Yorihiro Nishimura,Hiroyuki Shimizu,Marycelin Baba,Adekunle J. Adeniji,A. J. Williams,David R. Kilpatrick,M. S. Oberste,Steve Wassilak,Oyewale Tomori,Mark A. Pallansch,Olen M. Kew +27 more
TL;DR: It is estimated from the poliomyelitis case count and the paralytic case-to-infection ratio for type 2 wild poliovirus infections that ∼700,000 cVDPV2 infections have occurred during the outbreak.
Journal ArticleDOI
Enterovirus 71 Binding to PSGL-1 on Leukocytes: VP1-145 Acts as a Molecular Switch to Control Receptor Interaction
Yorihiro Nishimura,Hyunwook Lee,Susan Hafenstein,Chikako Kataoka,Takaji Wakita,Jeffrey M. Bergelson,Jeffrey M. Bergelson,Hiroyuki Shimizu +7 more
TL;DR: It is proposed that conserved lysine residues on the virus surface are responsible for interaction with sulfated tyrosine residues at the PS GL-1 N-terminus, and that VP1-145 acts as a switch, controlling PSGL-1 binding by modulating the exposure ofVP1-244K.