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Yoshitaka Matsuo
Researcher at Tohoku University
Publications - 25
Citations - 974
Yoshitaka Matsuo is an academic researcher from Tohoku University. The author has contributed to research in topics: Ribosome & Ribosome profiling. The author has an hindex of 7, co-authored 15 publications receiving 575 citations. Previous affiliations of Yoshitaka Matsuo include Heidelberg University.
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Journal ArticleDOI
Ubiquitination of stalled ribosome triggers ribosome-associated quality control
Yoshitaka Matsuo,Ken Ikeuchi,Yasushi Saeki,Shintaro Iwasaki,Christian Schmidt,Tsuyoshi Udagawa,Fumiya Sato,Hikaru Tsuchiya,Thomas Becker,Keiji Tanaka,Nicholas T. Ingolia,Roland Beckmann,Toshifumi Inada +12 more
TL;DR: It is reported that ubiquitination of the 40S ribosomal protein uS10 by the E3 ubiquitin ligase Hel2 (or RQT1) is required for RQC.
Journal ArticleDOI
Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways.
Ken Ikeuchi,Petr Tesina,Yoshitaka Matsuo,Takato Sugiyama,Jingdong Cheng,Yasushi Saeki,Keiji Tanaka,Thomas Becker,Roland Beckmann,Toshifumi Inada +9 more
TL;DR: It is reported that Hel2‐dependent uS10 ubiquitination and Slh1/Rqt2 are crucial for RQC and NGD induction within a di‐ribosome (disome) unit, which consists of the leading stalled ribosome and the following colliding ribosomes.
Journal ArticleDOI
The Ccr4-Not complex monitors the translating ribosome for codon optimality.
Robert Buschauer,Yoshitaka Matsuo,Takato Sugiyama,Ying Hsin Chen,Najwa Alhusaini,Thomas J. Sweet,Ken Ikeuchi,Ken Ikeuchi,Jingdong Cheng,Yasuko Matsuki,Risa Nobuta,Andrea Gilmozzi,Otto Berninghausen,Petr Tesina,Thomas Becker,Jeff Coller,Toshifumi Inada,Roland Beckmann +17 more
TL;DR: Insight is gained into the connection between the Ccr4-Not complex and the translation machinery in the context of mRNA homeostasis by combining cryo–electron microscopy, ribosome profiling, and biochemical analysis.
Journal ArticleDOI
Coupled GTPase and remodelling ATPase activities form a checkpoint for ribosome export
Yoshitaka Matsuo,Sander Granneman,Matthias Thoms,Rizos Georgios Manikas,David Tollervey,Ed Hurt +5 more
TL;DR: It is shown that a conserved Saccharomyces cerevisiae GTPase Nug2 has a key role in the timing of export competence, with release from its placeholder site linked to recruitment of the nuclear export machinery.
Journal ArticleDOI
RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1.
Yoshitaka Matsuo,Petr Tesina,Shizuka Nakajima,Masato Mizuno,Akinori Endo,Robert Buschauer,Jingdong Cheng,Okuto Shounai,Ken Ikeuchi,Yasushi Saeki,Thomas Becker,Roland Beckmann,Toshifumi Inada +12 more
TL;DR: Identification of SDD1 messenger RNA from Saccharomyces cerevisiae as an endogenous RQC substrate allows analysis of the mechanism underlying translational stalling and Hel2-dependent polyubiquitination of collided ribosomes to provide insight into ribosome dissociation.