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Young Bae Choi

Researcher at Chungbuk National University

Publications -  32
Citations -  304

Young Bae Choi is an academic researcher from Chungbuk National University. The author has contributed to research in topics: Transplantation & Autologous stem-cell transplantation. The author has an hindex of 8, co-authored 32 publications receiving 217 citations. Previous affiliations of Young Bae Choi include Samsung Medical Center & Chung-Ang University.

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NUDT15 Variants Cause Hematopoietic Toxicity with Low 6-TGN Levels in Children with Acute Lymphoblastic Leukemia.

TL;DR: NUDT15 genotyping should be conducted before administering thiopurine, and dose adjustments require caution regardless of 6-TGN levels, as these variants cause hematopoietic toxicity with low 6- TGN levels.
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Immunosuppressive therapy versus alternative donor hematopoietic stem cell transplantation for children with severe aplastic anemia who lack an HLA-matched familial donor.

TL;DR: Results suggest that frontline alternative donor HSCT may be a better treatment option than IST for children and adolescents with SAA who lack a human leukocyte Ag-matched familial donor.
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Tandem High-Dose Chemotherapy and Autologous Stem Cell Transplantation for Atypical Teratoid/Rhabdoid Tumor.

TL;DR: The required dose of craniospinal RT might be reduced in older patients if the intensity of chemotherapy is increased, however, early administration of RT should be considered to prevent early progression in young patients.
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Toxicity of tandem high-dose chemotherapy and autologous stem cell transplantation using carboplatin-thiotepa-etoposide and cyclophosphamide-melphalan regimens for malignant brain tumors in children and young adults.

TL;DR: It is demonstrated that tandem HDCT/auto-SCT using CTE/CM regimens was generally feasible, however, dose reduction during the second HDCT /auto- SCT in young children might be needed to decrease the death rate from toxicity.