Yu-An Cao

TL;DR: In this paper, the authors transplanted luciferase-labeled allogeneic splenocytes and monitored tissue distribution by in vivo bioluminescence imaging, showing that transplantation of purified naive T cells caused GVHD that was initiated in secondary lymphoid organs followed by target organ manifestation in gut, liver, and skin.

TL;DR: The MSCs‐R can selectively localize, survive, and proliferate in both subcutaneous tumor and lung metastasis as evidenced by noninvasive bioluminescence imaging and ex vivo validation.

TL;DR: In utero AAV-mediated gene transfer in this animal model demonstrates that novel therapeutic vectors and strategies can be rapidly tested in vivo and that rAAV may be developed to ameliorate genetic diseases with perinatal morbidity and mortality.

TL;DR: It is demonstrated that systemically delivered BMMCs preferentially home to and are retained by injured myocardium, demonstrating that molecular imaging can be used to successfully track BMMC therapy in murine models of heart disease.

TL;DR: It is concluded that the CLZN analogs that are presently available vary with respect to hRluc utilization in culture and in vivo, and that the effective use ofCLZN-utilizing enzymes in living animals depends on the selection of an appropriate substrate.