Y
Yu Han Chen
Researcher at Emory University
Publications - 1
Citations - 347
Yu Han Chen is an academic researcher from Emory University. The author has contributed to research in topics: Nuclear pore & C9orf72. The author has an hindex of 1, co-authored 1 publications receiving 241 citations.
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TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD
Ching Chieh Chou,Yi Zhang,Yi Zhang,Mfon E. Umoh,Spencer Vaughan,Ileana Lorenzini,Feilin Liu,Melissa Sayegh,Paul G. Donlin-Asp,Paul G. Donlin-Asp,Yu Han Chen,Duc M. Duong,Nicholas T. Seyfried,Maureen A. Powers,Thomas Kukar,Chadwick M. Hales,Marla Gearing,Nigel J. Cairns,Kevin B. Boylan,Dennis W. Dickson,Rosa Rademakers,Yong Jie Zhang,Leonard Petrucelli,Rita Sattler,Daniela C. Zarnescu,Jonathan D. Glass,Wilfried Rossoll,Wilfried Rossoll +27 more
TL;DR: BioID uses proximity-dependent biotin identification to interrogate the interactome of detergent-insoluble TDP-43 aggregates and finds them enriched for components of the nuclear pore complex and nucleocytoplasmic transport machinery.