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Yuan C. Lee
Researcher at Johns Hopkins University
Publications - 298
Citations - 17230
Yuan C. Lee is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Oligosaccharide & Lectin. The author has an hindex of 65, co-authored 297 publications receiving 16531 citations. Previous affiliations of Yuan C. Lee include Colorado State University & National Tsing Hua University.
Papers
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Journal ArticleDOI
Carbohydrate analysis by a phenol-sulfuric acid method in microplate format.
Tatsuya Masuko,Akio Minami,Norimasa Iwasaki,Tokifumi Majima,Shin-Ichiro Nishimura,Yuan C. Lee +5 more
TL;DR: This work has modified and optimized the phenol-sulfuric acid method to use 96-well microplates for high throughput, to gain greater sensitivity, and to economize the reagents.
Journal ArticleDOI
Carbohydrate-Protein Interactions: Basis of Glycobiology
Yuan C. Lee,R. T. Lee +1 more
Journal ArticleDOI
Monosaccharide analysis of glycoconjugates by anion exchange chromatography with pulsed amperometric detection.
TL;DR: The method of anion exchange chromatography followed by pulsed amperometric detection with AE-PAD has been applied to the compositional analysis of glycoconjugates and approximately one less residue of Man than predicted was determined.
Journal ArticleDOI
Binding of synthetic oligosaccharides to the hepatic Gal/GalNAc lectin. Dependence on fine structural features.
Yuan C. Lee,R.Reid Townsend,Mark R. Hardy,Jörgen Lönngren,Jan Arnarp,Martin Haraldsson,H Lönn +6 more
TL;DR: It was found that the number of Gal residues/cluster and their branching mode are major determinants of binding affinity of ligands to the hepatic lectin on the surface of hepatocytes.
Journal ArticleDOI
Affinity enhancement by multivalent lectin-carbohydrate interaction.
Reiko T. Lee,Yuan C. Lee +1 more
TL;DR: In this review article, a number of examples are given and important factors in the multi-valent interactions that govern the degree of affinity enhancement are described that are related to glycoside cluster effect.