R.Reid Townsend

TL;DR: The method of anion exchange chromatography followed by pulsed amperometric detection with AE-PAD has been applied to the compositional analysis of glycoconjugates and approximately one less residue of Man than predicted was determined.

TL;DR: It was found that the number of Gal residues/cluster and their branching mode are major determinants of binding affinity of ligands to the hepatic lectin on the surface of hepatocytes.

TL;DR: High-performance liquid chromatography using pellicular quaternary amine-bonded resins was used to separate a variety of neutral, sialylated, and phosphorylated oligosaccharide mixtures using electrochemical response, and complete separation of the parent neutral structures was obtained.

TL;DR: Ten characterized sialylated oligosaccharides from bovine fetuin were chromatographed using high-performance anion-exchange chromatography with pulsed amperometric detection and the relative molar electrochemical responses for di, tri, tetra, and pentasialylation oligosACcharides were found to be similar.

TL;DR: An interface is described that allows the direct coupling of high-performance alkaline anion exchange liquid chromatography with thermospray mass spectrometry, and sensitivity studies show minimum detection limits for the test compounds to be in the microgram range.